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Review
. 2019 Sep 30;90(10-S):50-52.
doi: 10.23750/abm.v90i10-S.8759.

Monogenic hypertension

Vincenza Precone  1 , Geraldo Krasi, Giulia Guerri, Liborio Stuppia, Francesco Romeo, Marco Perrone, Carla Marinelli, Alessandra Zulian, Tiziano Dallavilla, Matteo Bertelli
Affiliations
Review

Monogenic hypertension

Vincenza Precone et al. Acta Biomed. .

Abstract

Hypertension is a significant public health problem. Thirty percent of cases are caused by a single genetic mutation. Hypertension is the predominant and usually the only manifestation in monogenic hypertension Monogenic hypertension may involve mineralcorticoid-dependent or -independent increase in Na+ transport. Diagnosis is based on routine physical examination, blood pressure measurement and laboratory analysis of renin, aldosterone, cortisol and potassium. Genetic testing is useful for confirming diagnosis and for differential diagnosis. Monogenic hypertension has autosomal dominant or autosomal recessive inheritance.

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Conflict of interest statement

Each author declares that he or she has no commercial associations (e.g. consultancies, stock ownership, equity interest, patent/licensing arrangement etc.) that might pose a conflict of interest in connection with the submitted article

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