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. 2021 Sep;35(17):2823-2830.
doi: 10.1080/14786419.2019.1672068. Epub 2019 Oct 2.

Antifungal activity of compounds from the stems of Dalbergia stipulacea against Pythium insidiosum

Priyapan Posri  1 , Jittra Suthiwong  1 , Yordhathai Thongsri  2 , Chavi Yenjai  1
Affiliations

Antifungal activity of compounds from the stems of Dalbergia stipulacea against Pythium insidiosum

Priyapan Posri et al. Nat Prod Res. 2021 Sep.

Abstract

Two new compounds, dalpulanone (1) and 2-hydroxyisomucronustyrene (2), were isolated from the stems of Dalbergia stipulacea. Fourteen known compounds (3-16) were also isolated. The chemical structures of all isolated compounds were elucidated using spectroscopic methods, including 1D-NMR, 2D-NMR, MS and IR data. Compound 4 displayed the strongest antifungal activity against Pythium insidiosum and had higher activity than the amphotericin-B standard.

Keywords: 2-hydroxyisomucronustyrene; Dalbergia stipulacea; Pythium insidiosum; dalpulanone.

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