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. 2019 Oct 4;68(39):865-869.
doi: 10.15585/mmwr.mm6839e2.

E-cigarette Product Use, or Vaping, Among Persons with Associated Lung Injury - Illinois and Wisconsin, April-September 2019

E-cigarette Product Use, or Vaping, Among Persons with Associated Lung Injury - Illinois and Wisconsin, April-September 2019

Isaac Ghinai et al. MMWR Morb Mortal Wkly Rep. .

Abstract

In July 2019, the Illinois Department of Public Health and the Wisconsin Department of Health Services launched a coordinated epidemiologic investigation after receiving reports of several cases of lung injury in previously healthy persons who reported electronic cigarette (e-cigarette) use, or vaping (1). This report describes features of e-cigarette product use by patients in Illinois and Wisconsin. Detailed patient interviews were conducted by telephone, in person, or via the Internet with 86 (68%) of 127 patients. Overall, 75 (87%) of 86 interviewed patients reported using e-cigarette products containing tetrahydrocannabinol (THC), and 61 (71%) reported using nicotine-containing products. Numerous products and brand names were identified by patients. Nearly all (96%) THC-containing products reported were packaged, prefilled cartridges, and 89% were primarily acquired from informal sources (e.g., friends, family members, illicit dealers, or off the street). In contrast, 77% of nicotine-containing products were sold as prefilled cartridges, and 83% were obtained from commercial vendors. The precise source of this outbreak is currently unknown (2); however, the predominant use of prefilled THC-containing cartridges among patients with lung injury associated with e-cigarette use suggests that they play an important role. While this investigation is ongoing, CDC recommends that persons consider refraining from using e-cigarette, or vaping, products, particularly those containing THC. Given the diversity of products reported and frequency of patients using both THC- and nicotine-containing e-cigarette products, additional methods such as product testing and traceback could help identify the specific cause of this outbreak.

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Conflict of interest statement

All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. No potential conflicts of interest were disclosed.

Figures

FIGURE
FIGURE
Frequently reported brand names of tetrahydrocannabinol (THC)- and nicotine-containing electronic cigarette (e-cigarette), or vaping, products,†,§ reported by patients with lung injury — Illinois and Wisconsin, 2019 * Two brands of cannabidiol are not shown (each brand reported by one patient). 30 other THC-containing brands (including three brands of THC wax for “dabbing”) were only reported by one patient each. § 22 other nicotine-containing brands were only reported by one patient each. Data are presented from interviews conducted with 86 of 127 patients with lung injury associated with e-cigarette use, or vaping.

References

    1. Layden JE, Ghinai I, Pray I, et al. Pulmonary illness related to e-cigarette use in Illinois and Wisconsin—preliminary report. New Engl J Med 2019. Epub September 6, 2019. https://www.nejm.org/doi/full/10.1056/NEJMoa1911614 - DOI - PubMed
    1. Perrine CG, Pickens CM, Boehmer TK, et al. Characteristics of a multistate outbreak of lung injury associated with e-cigarette use or vaping—United States, 2019. MMWR Morb Mortal Wkly Rep 2019;68(39). - PMC - PubMed
    1. Schier JG, Meiman JG, Layden J, et al.; CDC 2019 Lung Injury Response Group. Severe pulmonary disease associated with electronic-cigarette-product use—interim guidance. MMWR Morb Mortal Wkly Rep 2019;68:787–90. 10.15585/mmwr.mm6836e2 - DOI - PMC - PubMed
    1. Spindle T, Cone E, Schlienz N, et al. Urinary excretion profile of 11-nor-9-carboxy Δ9-tetrahydrocannabinol (THCCOOH) following smoked and vaporized cannabis administration in infrequent cannabis users. Journal of Analytical Toxicology, 2019;43:233–58. 10.1093/jat/bky104 - DOI - PMC - PubMed
    1. Johansson E, Halldin M. Urinary excretion half-life of Δtetrahydrocannabinol-7-oic acid in heavy marijuana users after smoking. Journal of Analytical Toxicology, 1989;13:218–223. 10.1093/jat/13.4.218 - DOI - PubMed