Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Oct 2;7(10):101.
doi: 10.3390/medsci7100101.

Polycystic Ovary Syndrome in Adolescence

Affiliations
Review

Polycystic Ovary Syndrome in Adolescence

Rebecca Deans. Med Sci (Basel). .

Abstract

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in females, and is characterized by ovulatory dysfunction, hyperandrogenism, and polycystic ovarian morphology based on ultrasound. Controversy surrounds the optimum diagnosis and management in the adolescent population. Many patients with adult PCOS present with pathognomonic symptoms as adolescents, and there is value in early diagnosis due to the associated long-term metabolic and reproductive health sequalae. A definitive diagnosis does not need to be made prior to implementing treatment in this group of young women. The practitioner who has an adolescent presenting with signs and symptoms of PCOS, has a unique opportunity to risk stratify, screen for co-morbidities, and implement early management strategies, many of which are lifestyle modifications, to help prevent long term morbidity associated with this disease.

Keywords: adolescence; polycystic ovary syndrome.

PubMed Disclaimer

Conflict of interest statement

The author declares no conflict of interest

References

    1. Bozdag G., Mumusoglu S., Zengin D., Karabulut E., Yildiz B.O. The prevalence and phenotypic features of polycystic ovary syndrome: A systematic review and meta-analysis. Hum. Reprod. 2016;31:2841–2855. doi: 10.1093/humrep/dew218. - DOI - PubMed
    1. Teede H.J., Misso M.L., Costello M.F., Dokras A., Laven J., Moran L., Piltonen T., Norman R.J. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Clin. Endocrinol. 2018;89:251–268. doi: 10.1111/cen.13795. - DOI - PMC - PubMed
    1. Caldwell A.S.L., Edwards M.C., Desai R., Jimenez M., Gilchrist R.B., Handelsman D.J., Walters K.A. Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome. Proc. Natl. Acad. Sci. USA. 2017;114:E3334–E3343. doi: 10.1073/pnas.1616467114. - DOI - PMC - PubMed
    1. Ibanez L., Oberfield S.E., Witchel S., Auchus R.J., Chang R.J., Codner E., Dabadghao P., Darendeliler F., Elbarbary N.S., Gambineri A., et al. An International Consortium Update: Pathophysiology, Diagnosis, and Treatment of Polycystic Ovarian Syndrome in Adolescence. Horm. Res. Paediatr. 2017;88:371–395. doi: 10.1159/000479371. - DOI - PubMed
    1. Azziz R., Carmina E., Dewailly D., Diamanti-Kandarakis E., Escobar-Morreale H.F., Futterweit W., Escobar-Morreale H.F., Futterweit W., Legro R.S., Norman R.J., et al. Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline. J. Clin. Endocrinol. Metab. 2006;91:4237–4245. doi: 10.1210/jc.2006-0178. - DOI - PubMed

LinkOut - more resources