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Review
. 2019 Sep 3;17(8):533-542.
doi: 10.18502/ijrm.v17i8.4818. eCollection 2019 Aug.

The prevalence of polycystic ovary syndrome in adolescents: A systematic review and meta-analysis

Marzieh Saei Ghare Naz  1 , Fahimeh Ramezani Tehrani  2 , Hamid Alavi Majd  3 , Fazlollah Ahmadi  4 , Giti Ozgoli  5 , Farzaneh Rashidi Fakari  6 , Vida Ghasemi  6
Affiliations
Review

The prevalence of polycystic ovary syndrome in adolescents: A systematic review and meta-analysis

Marzieh Saei Ghare Naz et al. Int J Reprod Biomed. .

Abstract

Background: Polycystic ovarian syndrome is an endocrine disorder with many complications. This syndrome is a growing concern among adolescents around the world, with varying reports of its prevalence in different parts of the world.

Objective: This study aimed to determine the prevalence of polycystic ovary syndrome in adolescents by a systematic review and meta-analysis.

Materials and methods: In this study, a search for published articles with an English language limitation and without a time limit was done in different databases (Scopus, PubMed, and Web of Science, Emabse and Cochrane) in January 2019. The 12 studies that met the criteria for entering a qualitative assessment scale of 5 and higher were subjected to systematic review and meta-analysis. Egger and Begg's tests were used to check the publication bias. Data were analyzed with STATA software, version 11.1.

Results: Twelve studies were included for meta-analysis. The total number of participants in the study was 149,477. The average quality score of all studies was 8.67 (range: 5-10). The prevalence of polycystic ovarian syndrome in adolescents based on the Rotterdam criteria was 11.04% (95% CI: 6.84-16.09%), based on the National Institute of Health criteria, it was 3.39% (95% CI: 0.28-9.54%), and based on Androgen Excess and Polycystic Ovary Syndrome Society, it was 8.03% (95% CI: 6.24-10.01%).

Conclusion: The result of this study showed that there is a variation in the prevalence of PCOS in adolescents based on different criteria; we suggest more community-based studies among adolescences in different parts of the world.

Keywords: Adolescence; Meta-analysis; Polycystic ovary syndrome; Prevalence.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flow diagram of included studies.
Figure 2
Figure 2
The prevalence of polycystic ovary syndrome (NIH criteria) by researcher, year, prevalence and 95% confidence interval in the world.
Figure 3
Figure 3
The prevalence of polycystic ovary syndrome (Rotterdam criteria) by researcher, year, prevalence and 95% confidence interval in the world.
Figure 4
Figure 4
Funnel plot for checking publication bias.
See this image and copyright information in PMC

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