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Comment
. 2019 Oct 3;179(2):287-289.
doi: 10.1016/j.cell.2019.09.013.

Acid Tongues Cause Sour Thoughts

Affiliations
Comment

Acid Tongues Cause Sour Thoughts

Michael J Krashes et al. Cell. .

Abstract

Animals use their sense of taste to evaluate the quality and safety of food before ingestion. In this issue of Cell, Zhang and colleagues provide a comprehensive exploration into the elusive mechanisms underlying sour detection.

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Figures

Figure 1.
Figure 1.
A Dedicated Pathway for Sour Taste

Comment on

  • Sour Sensing from the Tongue to the Brain.
    Zhang J, Jin H, Zhang W, Ding C, O'Keeffe S, Ye M, Zuker CS. Zhang J, et al. Cell. 2019 Oct 3;179(2):392-402.e15. doi: 10.1016/j.cell.2019.08.031. Epub 2019 Sep 19. Cell. 2019. PMID: 31543264

References

    1. Barretto RP, Gillis-Smith S, Chandrashekar J, Yarmolinsky DA, Schnitzer MJ, Ryba NJ, and Zuker CS (2015). The neural representation of taste quality at the periphery. Nature 517, 373–376. - PMC - PubMed
    1. Chang RB, Waters H, and Liman ER (2010). A proton current drives action potentials in genetically identified sour taste cells. Proc. Natl. Acad. Sci. USA 107, 22320–22325. - PMC - PubMed
    1. Huang AL, Chen X, Hoon MA, Chandrashekar J, Guo W, Tränkner D, Ryba NJ, and Zuker CS (2006). The cells and logic for mammalian sour taste detection. Nature 442, 934–938. - PMC - PubMed
    1. Lee H, Macpherson LJ, Parada CA, Zuker CS, and Ryba NJP (2017). Rewiring the taste system. Nature 548, 330–333. - PMC - PubMed
    1. Liman ER, Zhang YV, and Montell C. (2014). Peripheral coding of taste. Neuron 81, 984–1000. - PMC - PubMed

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