Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Oct;36(10):1901-1909.
doi: 10.1111/echo.14495. Epub 2019 Oct 6.

Degenerative mitral valve stenosis: Diagnosis and management

Affiliations
Review

Degenerative mitral valve stenosis: Diagnosis and management

Ahmad Al-Taweel et al. Echocardiography. 2019 Oct.

Abstract

Mitral stenosis (MS) is a common valvular disease characterized by narrowing of the mitral valve orifice and a reduction in mitral valve area (MVA). While rheumatic MS (RMS) is frequently encountered in young individuals in developing countries, degenerative MS (DMS) is seen in the elderly in developed countries and its prevalence is increasing. DMS is usually a late presentation of mitral annular calcification (MAC). Accurate assessment of MVA in patients with MAC is challenging due to the alterations in the atrial and valvular structures as well as the presence of other comorbidities in this aging population. We will review the epidemiology, etiology, pathophysiology, diagnostic assessment, and management of DMS and compare the findings with RMS. The latest therapeutic approaches, including medical, surgical, and transcatheter valvular interventions, will be discussed.

Keywords: degenerative mitral stenosis; echocardiography; mitral annular calcification; mitral stenosis; valvular disease.

PubMed Disclaimer

References

REFERENCES

    1. Domenech B, Pomar JL, Prat-Gonzalez S, et al. Valvular heart disease epidemics. J Heart Valve Dis. 2016;25:1-7.
    1. Lung B, Baron G, Butchart EG, et al. A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease. Eur Heart J. 2003;24:1231-1243.
    1. Marijon E, Ou P, Celermajer DS, et al. Prevalence of rheumatic heart disease detected by echocardiographic screening. N Engl J Med. 2007;357:470-476.
    1. Baumgartner H, Hung J, Bermejo J, et al. Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice. J Am Soc Echocardiogr. 2009;22:1-23:quiz 101-2.
    1. Jain S, Mankad SV. Echocardiographic assessment of mitral stenosis: Echocardiographic features of rheumatic mitral stenosis. Cardiol Clin. 2013;31:177-191.

MeSH terms