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Review
. 2019 Nov;111(11):284-291.
doi: 10.1111/boc.201900069. Epub 2019 Oct 24.

The MYB-bHLH-WDR interferers (MBWi) epigenetically suppress the MBW's targets

Cuong Thach Nguyen  1 , Gia-Buu Tran  2 , Nguyen Hoai Nguyen  3
Affiliations
Review

The MYB-bHLH-WDR interferers (MBWi) epigenetically suppress the MBW's targets

Cuong Thach Nguyen et al. Biol Cell. 2019 Nov.

Abstract

Active repressors have been evidenced to function in different plant growth and development programs including hormonal signalling pathways. In Arabidopsis, the MYB-bHLH-WDR (MBW) complex is known to regulate different phenotypic traits such as anthocyanin biosynthesis, seed coat colour, trichome and root hair patterning. A number of transcription factors have been identified to play a negative role in the regulation of these traits via the interruption of MBW formation and function. Since these transcription factors work to interfere with the MBW complex, this review suggests their general name as MBW interferers (MBWi). Recent studies have shed light on the molecular mechanism of these MBWi and this review is aiming to provide a precise view of these MBWi. Moreover, from these, a new characteristic of active repressors is also updated.

Keywords: MBW; MBW interferers (MBWi); MYB; active repressor; transcription.

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References

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