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Multicenter Study
. 2020 Jan;95(1):E3-E5.
doi: 10.1002/ajh.25651. Epub 2019 Oct 17.

Bone marrow blast elimination by the fifth day of 7 + 3 induction is the strongest predictor of potential cure in patients with acute myeloid leukemia younger than 61 years of age: A long-term follow-up of a multi-center prospective study

Yishai Ofran  1   2 , Michal Hayun  1 , Ronit Leiba  3 , Tsila Zuckerman  1   2 , Netanel Horowitz  1   2 , Ron Hoffman  1   2 , Shimrit Ringelstein  1 , Noa Lavi  1   2 , Avraham Frisch  1 , Israel Henig  1 , Moshe E Gatt  4 , Ilana Hellmann  5 , Ariela Arad  4 , Shlomo Bulvik  6 , Ron Ram  7 , Sharon Gino-Moor  8 , Revital Saban  4 , Ariella Tvito  9 , Jacob M Rowe  1   2   9 , Chezi Ganzel  9
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Free article
Multicenter Study

Bone marrow blast elimination by the fifth day of 7 + 3 induction is the strongest predictor of potential cure in patients with acute myeloid leukemia younger than 61 years of age: A long-term follow-up of a multi-center prospective study

Yishai Ofran et al. Am J Hematol. 2020 Jan.
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REFERENCES

    1. Dohner H, Estey E, Grimwade D, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017;129(4):424-447.
    1. Gianfaldoni G, Mannelli F, Baccini M, Antonioli E, Leoni F, Bosi A. Clearance of leukaemic blasts from peripheral blood during standard induction treatment predicts the bone marrow response in acute myeloid leukaemia: a pilot study. Br J Haematol. 2006;134(1):54-57.
    1. Short NJ, Benton CB, Chen HC, et al. Peripheral blood blast clearance is an independent prognostic factor for survival and response to acute myeloid leukemia induction chemotherapy. Am J Hematol. 2016;91(12):1221-1226.
    1. Elliott MA, Litzow MR, Letendre LL, et al. Early peripheral blood blast clearance during induction chemotherapy for acute myeloid leukemia predicts superior relapse-free survival. Blood. 2007;110(13):4172-4174.
    1. Ofran Y, Leiba R, Ganzel C, et al. Prospective comparison of early bone marrow evaluation on day 5 versus day 14 of the “3 + 7” induction regimen for acute myeloid leukemia. Am J Hematol. 2015;90(12):1159-1164.