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. 2019 Oct 7;22Suppl 02(Suppl 02):E190010.SUPL.2.
doi: 10.1590/1980-549720190010.supl.2. eCollection 2019.

Evaluation of renal function in the Brazilian adult population, according to laboratory criteria from the National Health Survey

[Article in Portuguese, English]
Deborah Carvalho Malta  1   2 , Ísis Eloah Machado  2 , Cimar Azeredo Pereira  3 , André Willian Figueiredo  3 , Lilian Kelen de Aguiar  2   4 , Wanessa da Silva de Almeida  5 , Maria de Fatima Marinho de Souza  6 , Luiz Gastão Rosenfeld  7 , Célia Landman Szwarcwald  5
Affiliations
Free article

Evaluation of renal function in the Brazilian adult population, according to laboratory criteria from the National Health Survey

[Article in Portuguese, English]
Deborah Carvalho Malta et al. Rev Bras Epidemiol. .
Free article

Abstract
in English, Portuguese

Objective: To evaluate the renal function of the Brazilian adult population, according to laboratory criteria of the National Health Survey (Pesquisa Nacional de Saúde - PNS).

Methodology: A descriptive study was carried out with laboratory data from the PNS, which was collected between the years 2014 and 2015. Population prevalence of the serum creatinine (CR) and estimated glomerular filtration rate (GFR) according to sociodemographic variables, were analyzed from the PNS laboratory data.

Results: The sample consisted of 8,535 individuals aged 18 years old or older for the study of CR and 7,457 for the study of GFR. The GFR prevalence < 60 mL/min/1.73 m2 was 6.7% (95%CI 6.0 - 7.4), higher in women (8.2% 95%CI 7.2 - 9.2) than in men (5.0% 95%CI 4.2 - 6.0) p < 0.001, and in elderly > 60 years old it was 21.4%. For the values of CR ≥ 1.3 mg/dL in men were 5.5% (95%CI 4.6 - 6.5), and in women values of CR ≥ 1.1 mg/dL were 4.6% (95%CI 4.0 - 5.4), with no diference between the genders, p = 0.140.

Conclusion: Results from the PNS laboratory identified a higher prevalence of chronic kidney disease in the Brazilian population than that estimated in self-reported studies, with higher GFR < 60 mL/min/1.73 m2 in women, and reaching one fifth of the elderly. These tests may be useful for the purpose of identifying the disease early on and thus preventing the progression of renal damage and reduce the risk of cardiovascular events and mortality.

Objetivo: O presente estudo avaliou a função renal da população adulta brasileira, segundo critérios laboratoriais da Pesquisa Nacional de Saúde (PNS).

Metodologia: Estudo descritivo realizado com os dados laboratoriais da PNS, coletados entre os anos de 2014 e 2015. Com base nos dados laboratoriais foram analisadas prevalências populacionais de creatinina sérica (CR) e estimativa da taxa de filtração glomerular (TFG), segundo variáveis sociodemográficas.

Resultados: A amostra foi de 8.535 indivíduos com idade de 18 anos ou mais para o estudo da CR e de 7.457 indivíduos para o estudo de TFG. A prevalência TFG < 60 mL/min/1,73 m2 foi de 6,7% (IC95% 6,0 - 7,4), foi mais elevada em mulheres (8,2% IC95% 7,2 - 9,2) do que em homens (5,0% IC95% 4,2 - 6,0) p < 0,001 e em idosos ≥ 60 anos foi de 21,4%. Os valores de CR ≥ 1,3 mg/dL em homens foram 5,5% (IC95% 4,6 - 6,5) e em mulheres foram de CR ≥ 1,1 mg/dL, de 4,6% (IC95% 4,0- 5,4), sem diferença estatística significativa nos valores de CR entre sexo, p = 0,140.

Conclusão: Resultados laboratoriais da PNS identificaram prevalências mais elevadas da doença renal crônica na população brasileira do que o estimado em estudos autorreferidos. ATFG < 60 mL/min/1,73 m2 é mais elevada em mulheres e atinge um quinto dos idosos. Esses exames podem ser úteis no propósito de identificar precocemente a doença e, dessa forma, prevenir a progressão da lesão renal e reduzir o risco de eventos cardiovasculares e de mortalidade.

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