Upfront Chemotherapy Followed by Chemoradiation Remains the Sequence of Choice for Total Neoadjuvant Chemotherapy for Locally Advanced Rectal Cancer

Affiliations

Comment

Ahmed Abdalla et al. J Clin Oncol. 2019.

. 2019 Dec 20;37(36):3561-3562.

doi: 10.1200/JCO.19.01722. Epub 2019 Oct 9.

¹ Ahmed Abdalla, MD, and Amr Aref, MD, Ascension St John Hospital and Medical Center, Detroit, MI.

No abstract available

Comment in

Reply to A. Abdalla et al.
Fokas E, Rödel C; German Rectal Cancer Study Group. Fokas E, et al. J Clin Oncol. 2019 Dec 20;37(36):3562-3563. doi: 10.1200/JCO.19.02179. Epub 2019 Oct 9. J Clin Oncol. 2019. PMID: 31596636 No abstract available.

Randomized Phase II Trial of Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: CAO/ARO/AIO-12.
Fokas E, Allgäuer M, Polat B, Klautke G, Grabenbauer GG, Fietkau R, Kuhnt T, Staib L, Brunner T, Grosu AL, Schmiegel W, Jacobasch L, Weitz J, Folprecht G, Schlenska-Lange A, Flentje M, Germer CT, Grützmann R, Schwarzbach M, Paolucci V, Bechstein WO, Friede T, Ghadimi M, Hofheinz RD, Rödel C; German Rectal Cancer Study Group. Fokas E, et al. J Clin Oncol. 2019 Dec 1;37(34):3212-3222. doi: 10.1200/JCO.19.00308. Epub 2019 May 31. J Clin Oncol. 2019. PMID: 31150315 Clinical Trial.