Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease

Annabelle Rodriguez¹, Bernardo L Trigatti², Chieko Mineo³, Darcy Knaack⁴, John T Wilkins⁵, Daisy Sahoo^{4

6}, Bela F Asztalos⁷, Samia Mora⁸, Marina Cuchel⁹, Henry J Pownall¹⁰, Corina Rosales¹⁰, Pascal Bernatchez¹¹, Amanda Ribeiro Martins da Silva¹², Godfrey S Getz¹³, Jacob L Barber¹⁴, Gregory C Shearer¹⁵, Angela M Zivkovic¹⁶, Uwe J F Tietge^{17

18}, Frank M Sacks¹⁹, Margery A Connelly²⁰, Michael N Oda²¹, W Sean Davidson²², Mary G Sorci-Thomas⁶, Tomas Vaisar²³, Giacomo Ruotolo²⁴, Kasey C Vickers²⁵, Catherine Martel²⁶

Affiliations

¹ From the Center for Vascular Biology, Department of Cell Biology, University of Connecticut Health, Farmington (A.R.).
² Department of Biochemistry and Biomedical Sciences, McMaster University, and Thrombosis and Atherosclerosis Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada (B.L.T.).
³ Center for Pulmonary and Vascular Biology, Department of Pediatrics and Cell Biology, University of Texas Southwestern Medical Center, Dallas (C.M.).
⁴ Department of Biochemistry (D.K., D.S.), Medical College of Wisconsin, Milwaukee.
⁵ Division of Cardiology, Departments of Medicine and of Preventive Medicine, Northwestern University, Chicago, IL (J.T.W.).
⁶ Division of Endocrinology (D.S., M.G.S.-T.), Medical College of Wisconsin, Milwaukee.
⁷ Human Nutrition Research Center, Tufts University, Boston, MA (B.F.A.).
⁸ Center for Lipid Metabolomics, Divisions of Preventive and Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (S.M.).
⁹ Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (M.C.).
¹⁰ Institute for Academic Medicine, Houston Methodist, Weill Cornell Medical College, Houston, TX (H.J.P., C.R.).
¹¹ Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Heart and Lung Innovation Centre, St Paul's Hospital, Vancouver, BC, Canada (P.B.).
¹² Institute of Chemistry, University of Sao Paulo, Brazil (A.R.M.d.S.).
¹³ Department of Pathology, University of Chicago, IL (G.S.G.).
¹⁴ Department of Exercise Science, University of South Carolina, Columbia (J.L.B.).
¹⁵ Department Nutritional Sciences, The Pennsylvania State University, University Park (G.C.S.).
¹⁶ Department of Nutrition, University California Davis (A.M.Z.).
¹⁷ Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden (U.J.F.T.).
¹⁸ Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital, Stockholm, Sweden (U.J.F.T.).
¹⁹ Harvard T.H. Chan School of Public Health, Boston, MA (F.M.S.).
²⁰ Laboratory Corporation of America Holdings (LabCorp), Morrisville, NC (M.A.C.).
²¹ DRx BioLogics, Inc, Fairfield, CA (M.N.O.).
²² Department of Pathology and Laboratory Medicine, University of Cincinnati, OH (W.S.D.).
²³ UW Medicine Diabetes Institute, University of Washington, Seattle (T.V.).
²⁴ Eli Lilly and Company, Indianapolis, IN (G.R.).
²⁵ Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN (K.C.V.).
²⁶ Montreal Heart Institute, Montreal and Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada (C.M.).

PMID: 31597448
PMCID: PMC6937204
DOI: 10.1161/ATVBAHA.119.313340

Review

Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease

Annabelle Rodriguez et al. Arterioscler Thromb Vasc Biol. 2019 Dec.

. 2019 Dec;39(12):2457-2467.

doi: 10.1161/ATVBAHA.119.313340. Epub 2019 Oct 10.

Authors

Affiliations

¹ From the Center for Vascular Biology, Department of Cell Biology, University of Connecticut Health, Farmington (A.R.).
² Department of Biochemistry and Biomedical Sciences, McMaster University, and Thrombosis and Atherosclerosis Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada (B.L.T.).
³ Center for Pulmonary and Vascular Biology, Department of Pediatrics and Cell Biology, University of Texas Southwestern Medical Center, Dallas (C.M.).
⁴ Department of Biochemistry (D.K., D.S.), Medical College of Wisconsin, Milwaukee.
⁵ Division of Cardiology, Departments of Medicine and of Preventive Medicine, Northwestern University, Chicago, IL (J.T.W.).
⁶ Division of Endocrinology (D.S., M.G.S.-T.), Medical College of Wisconsin, Milwaukee.
⁷ Human Nutrition Research Center, Tufts University, Boston, MA (B.F.A.).
⁸ Center for Lipid Metabolomics, Divisions of Preventive and Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (S.M.).
⁹ Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (M.C.).
¹⁰ Institute for Academic Medicine, Houston Methodist, Weill Cornell Medical College, Houston, TX (H.J.P., C.R.).
¹¹ Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Heart and Lung Innovation Centre, St Paul's Hospital, Vancouver, BC, Canada (P.B.).
¹² Institute of Chemistry, University of Sao Paulo, Brazil (A.R.M.d.S.).
¹³ Department of Pathology, University of Chicago, IL (G.S.G.).
¹⁴ Department of Exercise Science, University of South Carolina, Columbia (J.L.B.).
¹⁵ Department Nutritional Sciences, The Pennsylvania State University, University Park (G.C.S.).
¹⁶ Department of Nutrition, University California Davis (A.M.Z.).
¹⁷ Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden (U.J.F.T.).
¹⁸ Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital, Stockholm, Sweden (U.J.F.T.).
¹⁹ Harvard T.H. Chan School of Public Health, Boston, MA (F.M.S.).
²⁰ Laboratory Corporation of America Holdings (LabCorp), Morrisville, NC (M.A.C.).
²¹ DRx BioLogics, Inc, Fairfield, CA (M.N.O.).
²² Department of Pathology and Laboratory Medicine, University of Cincinnati, OH (W.S.D.).
²³ UW Medicine Diabetes Institute, University of Washington, Seattle (T.V.).
²⁴ Eli Lilly and Company, Indianapolis, IN (G.R.).
²⁵ Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN (K.C.V.).
²⁶ Montreal Heart Institute, Montreal and Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada (C.M.).

PMID: 31597448
PMCID: PMC6937204
DOI: 10.1161/ATVBAHA.119.313340

Abstract

The HDL (high-density lipoprotein) Workshop was established in 2009 as a forum for candid discussions among academic basic scientists, clinical investigators, and industry researchers about the role of HDL in cardiovascular disease. This ninth HDL Workshop was held on May 16 to 17, 2019 in Boston, MA, and included outstanding oral presentations from established and emerging investigators. The Workshop featured 5 sessions with topics that tackled the role of HDL in the vasculature, its structural complexity, its role in health and disease states, and its interaction with the intestinal microbiome. The highlight of the program was awarding the Jack Oram Award to the distinguished professor emeritus G.S. Getz from the University of Chicago. The tenth HDL Workshop will be held on May 2020 in Chicago and will continue the focus on intellectually stimulating presentations by established and emerging investigators on novel roles of HDL in cardiovascular and noncardiovascular health and disease states.

Keywords: American Heart Association; cardiovascular disease; cholesterol; health; lipoproteins.

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References

1. https://hdlworkshop.org/, accessed 08 August 2019.
1. 2018 AHA/ACC/AACBPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the management of blood cholesterol. Circulation. 2019;139:e1082–e1143. - PMC - PubMed
1. http://static.heart.org/riskcalc/app/index.html#!/baseline-risk, accessed July 08 2019.
1. https://www.framinghamheartstudy.org/fhs-risk-functions/hard-coronary-he..., accessed July 08 2019.
1. Voight BF, Peloso GM, Orho-Melander M, et al. Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomization study. Lancet. 2012;380:572–580. - PMC - PubMed

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Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease

Affiliations

Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease

Authors

Affiliations

Abstract

References

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Grants and funding

LinkOut - more resources

Full Text Sources

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Medical