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. 2020 Jan;166(1):30-33.
doi: 10.1099/mic.0.000860.

Microbe Profile: Pseudomonas aeruginosa: opportunistic pathogen and lab rat

Stephen P Diggle  1 , Marvin Whiteley  1
Affiliations

Microbe Profile: Pseudomonas aeruginosa: opportunistic pathogen and lab rat

Stephen P Diggle et al. Microbiology (Reading). 2020 Jan.

Erratum in

Abstract

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen and a model bacterium for studying virulence and bacterial social traits. While it can be isolated in low numbers from a wide variety of environments including soil and water, it can readily be found in almost any human/animal-impacted environment. It is a major cause of illness and death in humans with immunosuppressive and chronic conditions, and infections in these patients are difficult to treat due to a number of antibiotic resistance mechanisms and the organism's propensity to form multicellular biofilms.

Keywords: Genomics; Physiology; Pseudomonas aeruginosa.

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Conflict of interest statement

The authors declare that there are no conflicts of interest.

References

    1. Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, et al. Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature. 2000;406:959–964. doi: 10.1038/35023079. - DOI - PubMed
    1. Freschi L, Vincent AT, Jeukens J, Emond-Rheault JG, Kukavica-Ibrulj I, et al. The Pseudomonas aeruginosa Pan-Genome provides new insights on its population structure, horizontal gene transfer, and pathogenicity. Genome Biol Evol. 2019;11:109–120. doi: 10.1093/gbe/evy259. - DOI - PMC - PubMed
    1. Poulsen BE, Yang R, Clatworthy AE, White T, Osmulski SJ, et al. Defining the core essential genome of Pseudomonas aeruginosa . Proc Natl Acad Sci USA. 2019 - PMC - PubMed
    1. Elborn JS. Cystic fibrosis. The Lancet. 2016;388:2519–2531. doi: 10.1016/S0140-6736(16)00576-6. - DOI - PubMed
    1. Whiteley M, Diggle SP, Greenberg EP. Progress in and promise of bacterial quorum sensing research. Nature. 2017;551:313–320. doi: 10.1038/nature24624. - DOI - PMC - PubMed

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