Oxygen toxicity in major emergency surgery-anything new?

Göran Hedenstierna¹, Christian S Meyhoff^{2

3}

Affiliations

¹ Department of Medical Sciences, Clinical Physiology, Hedenstierna Laboratory, University Hospital, 75185, Uppsala, Sweden. goran.hedenstierna@medsci.uu.se.
² Department of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
³ Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

Göran Hedenstierna et al. Intensive Care Med. 2019 Dec.

. 2019 Dec;45(12):1802-1805.

doi: 10.1007/s00134-019-05787-8. Epub 2019 Oct 10.

Göran Hedenstierna¹, Christian S Meyhoff^{2

3}

¹ Department of Medical Sciences, Clinical Physiology, Hedenstierna Laboratory, University Hospital, 75185, Uppsala, Sweden. goran.hedenstierna@medsci.uu.se.
² Department of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
³ Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

No abstract available

Conflict of interest statement

The authors declare that they have no conflicts of interests.

1. de Jonge S, Egger M, Latif A, et al. Effectiveness of 80% vs 30–35% fraction of inspired oxygen in patients undergoing surgery: an updated systematic review and meta-analysis. Br J Anaesth. 2019;122(3):325–334. doi: 10.1016/j.bja.2018.11.024. - DOI - PubMed
1. Hedenstierna G, Meyhoff CS, Perchiazzi G, et al. Modification of the World Health Organization Global Guidelines for prevention of surgical site infection is needed. Anesthesiology. 2019;131(1):46–57. doi: 10.1097/ALN.0000000000002848. - DOI - PubMed
1. Staehr-Rye AK, Meyhoff CS, Scheffenbichler FT, et al. High intraoperative inspiratory oxygen fraction and risk of major respiratory complications. Br J Anaesth. 2017;119(1):140–149. doi: 10.1093/bja/aex128. - DOI - PubMed
1. Kurz A, Kopyeva T, Suliman I, et al. Supplemental oxygen and surgical-site infections: an alternating intervention controlled trial. Br J Anaesth. 2018;120(1):117–126. doi: 10.1016/j.bja.2017.11.003. - DOI - PubMed
1. Meyhoff CS, Wetterslev J, Jorgensen LN, et al. Effect of high perioperative oxygen fraction on surgical site infection and pulmonary complications after abdominal surgery: the PROXI randomized clinical trial. JAMA. 2009;302(14):1543–1550. doi: 10.1001/jama.2009.1452. - DOI - PubMed