Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Oct 9;17(10):571.
doi: 10.3390/md17100571.

Therapies from Fucoidan: New Developments

Helen J Fitton  1 , Damien S Stringer  2 , Ah Young Park  2 , Samuel N Karpiniec  2
Affiliations
Review

Therapies from Fucoidan: New Developments

Helen J Fitton et al. Mar Drugs. .

Abstract

Since our last review in 2015, the study and use of fucoidan has extended in several research areas. Clinical use of fucoidan for the treatment of renal disease has become available and human safety studies have been undertaken on radiolabeled fucoidan for the purpose of imaging thrombi. Fucoidan has been incorporated into an increasing number of commercially available supplements and topical treatments. In addition, new measuring techniques are now available to assess the biologically relevant uptake of fucoidans and to assist in production. Microbiome modulation and anti-pathogenic effects are increasingly promising applications for fucoidans, due to the need for alternative approaches to antibiotic use in the food chain. This review outlines promising new developments in fucoidan research, including potential future therapeutic use.

Keywords: analysis; fucoidan; microbiome; norovirus.

PubMed Disclaimer

Conflict of interest statement

“The authors are employees of Marinova Pty Ltd.”

References

    1. Fitton J.H., Stringer D.N., Karpiniec S.S. Therapies from Fucoidan: An Update. Mar. Drugs. 2015;13:5920–5946. doi: 10.3390/md13095920. - DOI - PMC - PubMed
    1. Wang Y., Xing M., Cao Q., Ji A., Liang H., Song S. Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies. Mar. Drugs. 2019;17:183. doi: 10.3390/md17030183. - DOI - PMC - PubMed
    1. Van Weelden G., Bobinski M., Okla K., van Weelden W.J., Romano A., Pijnenborg J.M.A. Fucoidan Structure and Activity in Relation to Anti-Cancer Mechanisms. Mar. Drugs. 2019;17:32. doi: 10.3390/md17010032. - DOI - PMC - PubMed
    1. Citkowska A., Szekalska M., Winnicka K. Possibilities of Fucoidan Utilization in the Development of Pharmaceutical Dosage Forms. Mar. Drugs. 2019;17:458. doi: 10.3390/md17080458. - DOI - PMC - PubMed
    1. Wang J., Geng L., Yue Y., Zhang Q. Use of fucoidan to treat renal diseases: A review of 15 years of clinic studies. Prog. Mol. Biol. Transl. Sci. 2019;163:95–111. doi: 10.1016/bs.pmbts.2019.03.011. - DOI - PubMed

LinkOut - more resources