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. 2019 Oct 11;14(10):e0223518.
doi: 10.1371/journal.pone.0223518. eCollection 2019.

Management strategies for vaccinated animals after an outbreak of foot-and-mouth disease and the impact on return to trade

Richard Bradhurst  1 , Graeme Garner  2 , Iain East  2 , Clare Death  2 , Aaron Dodd  1 , Tom Kompas  1
Affiliations

Management strategies for vaccinated animals after an outbreak of foot-and-mouth disease and the impact on return to trade

Richard Bradhurst et al. PLoS One. .

Abstract

An incursion of Foot-and-mouth disease (FMD) in a previously FMD-free country can cause significant economic damage from immediate and prolonged closure of FMD-sensitive markets. Whilst emergency vaccination may help contain disease, the presence of vaccinated animals complicates post-outbreak management and the recovery of FMD-free status for return to trade. We present enhancements to the Australian Animal DISease (AADIS) model that allow comparisons of post-outbreak management strategies for vaccinated animals, for the purposes of securing the earliest possible return to trade. Two case studies are provided that compare the retention of vaccinated animals with removal for waste/salvage, and the impact on recovery of FMD-sensitive markets per OIE guidelines. It was found that a vaccinate-and-retain strategy was associated with lower post-outbreak management costs, however this advantage was outweighed by significantly higher trade losses. Under the assumptions of the study there was no cost advantage to salvaging the removed vaccinated animals.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Infected herds (n = 18) in the simulated VIC FMD outbreak scenario at the end of the 14-day silent spread period.
Fig 2
Fig 2. Infected herds (n = 20) in the simulated WA FMD outbreak scenario at the end of the 14-day silent spread period.
Fig 3
Fig 3. Comparison of vaccination and non-vaccination control strategies for the VIC FMD outbreak scenario.
Fig 4
Fig 4. Control and post-outbreak managements costs for different post-outbreak management strategies in the VIC FMD outbreak scenario.
Fig 5
Fig 5. Loss of trade and total outbreak costs for different post-outbreak management strategies in the VIC FMD outbreak scenario.
Fig 6
Fig 6. Comparison of vaccination and non-vaccination control strategies for the WA FMD outbreak scenario.
Fig 7
Fig 7. Control and post-outbreak managements costs for different post-outbreak management strategies in the WA FMD outbreak scenario.
Fig 8
Fig 8. Loss of trade and total outbreak costs for different post-outbreak management strategies in the WA FMD outbreak scenario.
See this image and copyright information in PMC

References

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