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Review
. 2019 Jun 19;18(4):312-322.
doi: 10.1002/rmb2.12286. eCollection 2019 Oct.

The success of various endometrioma treatments in infertility: A systematic review and meta-analysis of prospective studies

Affiliations
Review

The success of various endometrioma treatments in infertility: A systematic review and meta-analysis of prospective studies

Saeed Alborzi et al. Reprod Med Biol. .

Abstract

Background: Endometriosis is seen in 0.5%-5% of fertile and 25%-40% of infertile women. To investigate this conflict between gynecologists that ovarian endometriomas should be removed or not before making any decision about pregnancy among infertile women, the authors decided to carry out a systematic review and meta-analysis to compare the effect of various available therapeutic methods and notice the impact of these options on women's pregnancy rate.

Methods: This review is based on PRISMA recommendations with an electronic search using the following databases: PubMed, Scopus, Google scholar, etc, from 2000 to 2018, in the English language. The studies compare pregnancy rate based on four different treatment types of OMAs between infertile women: (surgery + ART, surgery + spontaneous pregnancy, aspiration ± sclerotherapy + ART, and ART alone).

Main findings: At least eight prospective studies were included, in which 553 infertile women were compared in terms of treatment methods of OMAs before trying to become pregnant.

Conclusion: Treatments are usually based on the patient's clinical condition and must be individual, with the purpose of relieving pain, improving fertility, or both. The authors do not have not any significant difference between our four groups of study; however, the success of surgical procedure compared to other methods was higher and the success of ART alone was the least.

Keywords: endometriosis; female; infertility; pregnancy rate; reproduction.

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Conflict of interest statement

Conflict of interest: Saeed Alborzi, Ziba Zahiri Sorouri, Elham Askari, Tahereh Poordast, and Kefayat Chamanara declare that they have no conflict of interest. Human/animal rights statements and informed consent: This article does not contain any studies with human and animal patients performed by any of the authors.

Figures

Figure 1
Figure 1
Flowchart describing the study design process

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