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. 2019 Sep 24:10:1210.
doi: 10.3389/fphys.2019.01210. eCollection 2019.

Different Types of Physical Activity and Metabolic Control in People With Type 1 Diabetes Mellitus

Iztok Štotl  1 , Tim Kambič  2   3 , Vedran Hadžić  2 , Anže Zdolšek  2
Affiliations

Different Types of Physical Activity and Metabolic Control in People With Type 1 Diabetes Mellitus

Iztok Štotl et al. Front Physiol. .

Abstract

Background: The aim of presented cross-sectional study was to determine the association of different types of physical activity (PA) with metabolic control in people with type 1 diabetes.

Materials and methods: A total of 109 adult subjects with type 1 diabetes were asked to complete the non-exercise activity thermogenesis (NEAT) questionnaire, the hypoglycemia questionnaire, and the World Health Organization Global PA Questionnaire (GPAQ) which was used to assess moderate PA (MPA) and vigorous PA (VPA).

Results: NEAT score (p < 0.001) and total duration of work as assessed with GPAQ (p = 0.007) were positively associated with chronic glycemic control when controlled for sex, BMI, and continuous glucose monitoring system (CGMS) use. We could not confirm such association with total leisure time PA (LTPA) assessed with GPAQ (p = 0.443), though. Multivariate regression model controlled for sex showed positive effects of HbA1 c (p = 0.011) and age (p = 0.035), and negative effect of NEAT score (p = 0.001) on BMI. Systolic blood pressure was positively associated with duration of MPA (p = 0.009) and VPA (p = 0.012), but not with NEAT score (p = 0.830) when controlled for sex and BMI. NEAT score and VPA were positively associated with HDL levels when controlled for sex and BMI. Controlled for sex and BMI, higher values of VPA were significantly associated with lower levels of total cholesterol (p = 0.009) and LDL (p = 0.005).

Conclusion: Higher levels of NEAT are associated with some favorable metabolic effects in adult people with type 1 diabetes, but may also present an additional burden for them with more challenging environment regarding glycemic control.

Keywords: hypoglycemia; metabolism; obesity; physical activity; type 1 diabetes.

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