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Clinical Trial
. 2020 Mar;34(3):914-918.
doi: 10.1038/s41375-019-0589-3. Epub 2019 Oct 14.

Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial

Laura Cicconi #  1 , Uwe Platzbecker #  2 , Giuseppe Avvisati  3 , Francesca Paoloni  4 , Christian Thiede  5 , Marco Vignetti  4 , Paola Fazi  4 , Felicetto Ferrara  6 , Mariadomenica Divona  7 , Francesco Albano  8 , Fabio Efficace  4 , Marco Sborgia  9 , Eros Di Bona  10 , Massimo Breccia  11 , Erika Borlenghi  12 , Roberto Cairoli  13 , Alessandro Rambaldi  14 , Lorella Melillo  15 , Giorgio La Nasa  16 , Walter Fiedler  17 , Peter Brossart  18 , Bernd Hertenstein  19 , Helmut R Salih  20 , Ombretta Annibali  3 , Mohammed Wattad  21 , Michael Lubbert  22 , Christian H Brandts  23 , Mathias Hanel  24 , Christoph Rollig  5 , Norbert Schmitz  25 , Hartmut Link  26 , Chiara Frairia  27 , Claudio Fozza  28 , Alfonso Maria D'Arco  29 , Nicola Di Renzo  30 , Agostino Cortelezzi  31 , Francesco Fabbiano  32 , Konstanze Dohner  33 , Arnold Ganser  34 , Hartmut Dohner  33 , Sergio Amadori  4 , Franco Mandelli  4 , Maria Teresa Voso  35   36 , Gerhard Ehninger  5 , Richard F Schlenk  37 , Francesco Lo-Coco  1   38
Affiliations
Clinical Trial

Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial

Laura Cicconi et al. Leukemia. 2020 Mar.
No abstract available

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References

    1. Lo-Coco F, Avvisati G, Vignetti M, Breccia M, Gallo E, Rambaldi A, et al. Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: results of the AIDA-2000 trial of the GIMEMA group. Blood. 2010;116:3171–9. - DOI
    1. Sanz MA, Montesinos P, Rayón C, Holowiecka A, De La Serna J, Milone G, et al. Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome. Blood. 2010;115:5137–46. - DOI
    1. Sanz MA, Lo-Coco F. Modern approaches to treating acute promyelocytic leukemia. J Clin Oncol. 2010;29:495–503. - DOI
    1. Sanz MA, Fenaux P, Tallman MS, Estey EH, Löwenberg B, Naoe T, et al. Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet. Blood. 2019;133:1630–43. - DOI
    1. Montesinos P, González JD, González J, Rayón C, de Lisa E, Amigo ML, et al. Therapy-related myeloid neoplasms in patients with acute promyelocytic leukemia treated with all-trans-retinoic Acid and anthracycline-based chemotherapy. J Clin Oncol. 2010;28:3872–9. - DOI

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