Primary Cutaneous Gamma-Delta T-cell Lymphoma: Not an Aggressive Disease in All Cases

doi:10.2340/00015555-3340

Case Reports

. 2020 Jan 23;100(1):adv00035.

doi: 10.2340/00015555-3340.

Primary Cutaneous Gamma-Delta T-cell Lymphoma: Not an Aggressive Disease in All Cases

Mehdi Khallaayoune¹, Florent Grange, Morgane Condamina, Vanessa Szablewski, Bernard Guillot, Olivier Dereure

Affiliations

PMID: 31612963
PMCID: PMC9128963
DOI: 10.2340/00015555-3340

Case Reports

Primary Cutaneous Gamma-Delta T-cell Lymphoma: Not an Aggressive Disease in All Cases

Mehdi Khallaayoune et al. Acta Derm Venereol. 2020.

. 2020 Jan 23;100(1):adv00035.

doi: 10.2340/00015555-3340.

Authors

Mehdi Khallaayoune¹, Florent Grange, Morgane Condamina, Vanessa Szablewski, Bernard Guillot, Olivier Dereure

Affiliation

¹ department of Dermatology, University of Montpellier, 34295 Montpellier, France.

PMID: 31612963
PMCID: PMC9128963
DOI: 10.2340/00015555-3340

No abstract available

Keywords: gamma-delta T-cell lymphoma; indolent; primary cutaneous.

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Figures

**Fig. 1**
**Patient 1: multiple ulcerated nodules on the abdomen**.

See this image and copyright information in PMC

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A Previously Unrecognized Granulomatous Variant of Gamma-Delta T-Cell Lymphoma.
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Indolent cutaneous lymphoma with gamma/delta expression after COVID-19 vaccination.
Hobayan CG, Chung CG. Hobayan CG, et al. JAAD Case Rep. 2023 Feb;32:74-76. doi: 10.1016/j.jdcr.2022.12.001. Epub 2022 Dec 13. JAAD Case Rep. 2023. PMID: 36530557 Free PMC article. No abstract available.
Advances in classification and treatment of primary cutaneous lymphomas.
Zheng H, Qiu L, Liu C, Tian C. Zheng H, et al. Ann Hematol. 2025 Apr;104(4):2143-2157. doi: 10.1007/s00277-025-06311-3. Epub 2025 Mar 25. Ann Hematol. 2025. PMID: 40131416 Free PMC article. Review.
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References

1. Junkins-Hopkins JM. Aggressive cutaneous T-cell lymphomas. Sem Diag Pathol 2017; 34: 44–59. - PubMed
1. Guitart J, Weisenburger DD, Subtil A, Kim E, Wood G, Duvic M, et al. . Cutaneous γδ T-cell lymphomas: a spectrum of presentations with overlap with other cytotoxic lymphomas. Am J Surg Pathol 2012; 36: 1656–1665. - PubMed
1. Willemze R, Cerroni L, Kempf W, Berti E, Facchetti F, Swerdlow SH, et al. . The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas. Blood 2019; 133: 1703–1714. - PMC - PubMed
1. Benecke J, Géraud C, Nicolay JP. Cutaneous gamma-delta T-cell lymphoma with an initially indolent course mimicking lupus panniculitis. Acta Derm Venereol 2017; 97: 665–666. - PubMed
1. Ali L, Young MR, Bayerl MG, Helm KF, Clarke LE. Gammadelta T-cell lymphoma arisingin a long-standing cutaneous plaque. J Cutan Pathol 2015; 42: 987–991. - PubMed

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[1] Junkins-Hopkins JM. Aggressive cutaneous T-cell lymphomas. Sem Diag Pathol 2017; 34: 44–59. - PubMed

[2] Junkins-Hopkins JM. Aggressive cutaneous T-cell lymphomas. Sem Diag Pathol 2017; 34: 44–59. - PubMed

[3] Guitart J, Weisenburger DD, Subtil A, Kim E, Wood G, Duvic M, et al. . Cutaneous γδ T-cell lymphomas: a spectrum of presentations with overlap with other cytotoxic lymphomas. Am J Surg Pathol 2012; 36: 1656–1665. - PubMed

[4] Guitart J, Weisenburger DD, Subtil A, Kim E, Wood G, Duvic M, et al. . Cutaneous γδ T-cell lymphomas: a spectrum of presentations with overlap with other cytotoxic lymphomas. Am J Surg Pathol 2012; 36: 1656–1665. - PubMed

[5] Willemze R, Cerroni L, Kempf W, Berti E, Facchetti F, Swerdlow SH, et al. . The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas. Blood 2019; 133: 1703–1714. - PMC - PubMed

[6] Willemze R, Cerroni L, Kempf W, Berti E, Facchetti F, Swerdlow SH, et al. . The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas. Blood 2019; 133: 1703–1714. - PMC - PubMed

[7] Benecke J, Géraud C, Nicolay JP. Cutaneous gamma-delta T-cell lymphoma with an initially indolent course mimicking lupus panniculitis. Acta Derm Venereol 2017; 97: 665–666. - PubMed

[8] Benecke J, Géraud C, Nicolay JP. Cutaneous gamma-delta T-cell lymphoma with an initially indolent course mimicking lupus panniculitis. Acta Derm Venereol 2017; 97: 665–666. - PubMed

[9] Ali L, Young MR, Bayerl MG, Helm KF, Clarke LE. Gammadelta T-cell lymphoma arisingin a long-standing cutaneous plaque. J Cutan Pathol 2015; 42: 987–991. - PubMed

[10] Ali L, Young MR, Bayerl MG, Helm KF, Clarke LE. Gammadelta T-cell lymphoma arisingin a long-standing cutaneous plaque. J Cutan Pathol 2015; 42: 987–991. - PubMed

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Primary Cutaneous Gamma-Delta T-cell Lymphoma: Not an Aggressive Disease in All Cases

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Primary Cutaneous Gamma-Delta T-cell Lymphoma: Not an Aggressive Disease in All Cases

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