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Ghrelin is a peptide hormone known for its role in the stimulation of appetite and feeding behavior, energy homeostasis, and carbohydrate metabolism. Ghrelin’s orexigenic (appetite-stimulating) effects get mediated via metabolic need-driven homeostatic feeding as well as central actions on reward, memory, and motivated feeding behavior. Having only been recently discovered in 1999, ghrelin’s many putative functions have sparked interest in a variety of clinical applications. This brief review focuses on the significant effects of ghrelin.
Makris MC, Alexandrou A, Papatsoutsos EG, Malietzis G, Tsilimigras DI, Guerron AD, Moris D. Ghrelin and Obesity: Identifying Gaps and Dispelling Myths. A Reappraisal. In Vivo. 2017 Nov-Dec;31(6):1047-1050.
-
PMC
-
PubMed
Koutouratsas T, Kalli T, Karamanolis G, Gazouli M. Contribution of ghrelin to functional gastrointestinal disorders' pathogenesis. World J Gastroenterol. 2019 Feb 07;25(5):539-551.
-
PMC
-
PubMed
Yanagi S, Sato T, Kangawa K, Nakazato M. The Homeostatic Force of Ghrelin. Cell Metab. 2018 Apr 03;27(4):786-804.
-
PubMed
Tauber M, Coupaye M, Diene G, Molinas C, Valette M, Beauloye V. Prader-Willi syndrome: A model for understanding the ghrelin system. J Neuroendocrinol. 2019 Jul;31(7):e12728.
-
PubMed
Lv Y, Liang T, Wang G, Li Z. Ghrelin, a gastrointestinal hormone, regulates energy balance and lipid metabolism. Biosci Rep. 2018 Oct 31;38(5)
-
PMC
-
PubMed
