Neuroanatomy, Neural Crest

Excerpt

The neural crest is a collection of multipotent stem cells located at the side of the neural tube proximal to the epidermal layer after neurulation. These cells migrate throughout the embryo using a variety of mechanisms and give rise to a large range of cell types. Given the diversity of the cells that arise from the neural crest, its pathologies, known as neurocristopathies, can affect many different systems.

Understanding the complex methods behind neural crest cell migration, differentiation, and pathology can help with better understanding both human and cell development. The multipotency of neural crest stem cells also provides interesting avenues for research and potential medical applications. The presence of a neural crest is a defining feature of vertebrates, and researchers often employ animal models in neural crest research.