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Review
. 2019 Dec;20(12):746-762.
doi: 10.1038/s41583-019-0223-4. Epub 2019 Oct 15.

Oscillating circuitries in the sleeping brain

Antoine R Adamantidis  1   2 , Carolina Gutierrez Herrera  3   4 , Thomas C Gent  3   5
Affiliations
Review

Oscillating circuitries in the sleeping brain

Antoine R Adamantidis et al. Nat Rev Neurosci. 2019 Dec.

Abstract

Brain activity during sleep is characterized by circuit-specific oscillations, including slow waves, spindles and theta waves, which are nested in thalamocortical or hippocampal networks. A major challenge is to determine the relationships between these oscillatory activities and the identified networks of sleep-promoting and wake-promoting neurons distributed throughout the brain. Improved understanding of the neurobiological mechanisms that orchestrate sleep-related oscillatory activities, both in time and space, is expected to generate further insight into the delineation of sleep states and their functions.

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