Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019;65(Supplement):S180-S184.
doi: 10.3177/jnsv.65.S180.

Absorption and Metabolism of γ-Oryzanol, a Characteristic Functional Ingredient in Rice Bran

Kazue Sawada  1   2 , Halida Rahmania  1 , Midori Matsuki  2 , Hiroyuki Hashimoto  2 , Junya Ito  1 , Teruo Miyazawa  3   4 , Kiyotaka Nakagawa  1
Affiliations
Review

Absorption and Metabolism of γ-Oryzanol, a Characteristic Functional Ingredient in Rice Bran

Kazue Sawada et al. J Nutr Sci Vitaminol (Tokyo). 2019.

Abstract

γ-Oryzanol (OZ), a functional substance found in rice bran, consists of multiple molecular species. In both in vitro and in vivo studies, the researches exploring the various function of rice bran OZ have been conducted for a long time, and it has become clear that OZ has a lot of pharmaceutical activities. It is assumed that each type of OZ molecular species may have different effects. In contrast, the profile behaviour of OZ inside the body has not been fully understood. This article reviews the previous studies about the digestion, absorption, metabolism, and effects of rice bran OZ and also introduces the new method to evaluate the OZ metabolic fate by using high-performance liquid chromatography (HPLC) combined with tandem mass-spectrometry (MS/MS) which has higher selectivity and sensitivity.

Keywords: HPLC-MS/MS; absorption and metabolism; rice bran oil; γ-oryzanol.

PubMed Disclaimer