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Review
. 2019 Sep 5;10(3):e8.
doi: 10.5037/jomr.2019.10308. eCollection 2019 Jul-Sep.

Dental Implant Outcomes in Grafted Sockets: a Systematic Review and Meta-Analysis

Affiliations
Review

Dental Implant Outcomes in Grafted Sockets: a Systematic Review and Meta-Analysis

Ausra Ramanauskaite et al. J Oral Maxillofac Res. .

Abstract

Objectives: To assess the treatment outcomes of the dental implants placed in the grafted sockets.

Material and methods: A search protocol was developed to evaluate the treatment outcomes of dental implants placed in the grafted sockets in terms of implant survival rates (primary outcome), marginal-bone-level (MBL) changes, clinical parameters (i.e., bleeding on probing, probing depth), occurrence of peri-implant diseases, and aesthetic outcomes (secondary outcomes). Randomized controlled clinical trials (RCTs), controlled clinical trials, and prospective studies with at least 12 months of follow-up and a minimum of 10 patients having at least one dental implant inserted into the grafted socket were conducted. MEDLINE (PubMed) was searched for relevant articles published until 1st April 2019. A meta-analysis was performed using the random-effects model on the selected qualifying articles.

Results: The present analysis included 7 RCTs. The survival rate of the implants inserted into the grafted sockets ranged from 95 to 100% after 1 to 4 years of follow-up. MBL loss was found to be significantly greater for the implants placed in the non-grafted healed sites than for those placed in the previously grafted sockets (weighted mean difference = -1.961 mm, P < 0.0001). In terms of MBL changes, no difference was detected between immediately inserted implants versus implants placed in previously grafted sockets. None of the included studies reported on the clinical parameters or occurrence of peri-implant diseases.

Conclusions: Implants inserted into the previously grafted sockets showed high survival rates and lower marginal-bone-level loss than the implants inserted into the non-grafted sites.

Keywords: alveolar bone atrophy; alveolar bone grafting; dental implants; tooth socket.

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Figures

Figure 1
Figure 1
PRISMA 2009 flow diagram.
Figure 2
Figure 2
Forest plot of odds ratio (95% CI) for marginal bone level changes between the implants placed in the grafted sockets and implants inserted in previously non-grafted sites. CI = confidence interval; SMD = standardized mean difference; N1 = implants placed in the grafted sockets; N2 = implants inserted in previously non-grafted sites; df = degrees of freedom; Q = heterogeneity test.
Figure 3
Figure 3
Forest plot of odds ratio (95% CI) for marginal-bone-level changes between the implants placed in grafted sockets and immediate implant placement. CI = confidence interval; SMD = standardized mean difference; N1 = implants placed in grafted sockets; N2 = immediate implant placement; df = degrees of freedom; Q = heterogeneity test.

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