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Comment
. 2019 Dec;35(12):883-885.
doi: 10.1016/j.tig.2019.09.002. Epub 2019 Oct 14.

Gene Regulation Knows Its Boundaries

Elzo de Wit  1
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Gene Regulation Knows Its Boundaries

Elzo de Wit. Trends Genet. 2019 Dec.

Abstract

The genome is folded nonrandomly inside the cell nucleus. How this contributes to gene regulation is an important subject of investigation. A new study by Despang et al. shows how the spatial segregation of genes and regulatory regions can influence developmental expression in subtle, but critical ways.

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