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Comparative Study
. 2019 Nov;14(6):958-962.
doi: 10.1111/chd.12851. Epub 2019 Oct 18.

Impact of durable ventricular assist devices on post-transplant outcomes in adults with congenital heart disease

Ari Cedars  1 , Luke Burchill  2 , S Lucy Roche  3 , Jonathan Menachem  4 , Kelly Axsom  5 , Kristen Tecson  6 ; ACTION Learning Network, Adult Congenital Heart Disease Sub-Committee
Affiliations
Comparative Study

Impact of durable ventricular assist devices on post-transplant outcomes in adults with congenital heart disease

Ari Cedars et al. Congenit Heart Dis. 2019 Nov.

Abstract

Background: There are no published data on post-transplant outcomes in durable ventricular assist device (VAD)-supported adult congenital heart disease (ACHD) patients.

Methods: We compared post-transplant outcomes in VAD-supported vs non-VAD-supported ACHD patients using the Scientific Registry of Transplant Recipients.

Results: At 1 year, there was no difference in post-transplant mortality between VAD-supported (12 patients) and non-VAD-supported (671 patients) ACHD patients.

Conclusions: In appropriate ACHD patients, VAD use as a bridge to transplant is a reasonable strategy.

Keywords: adult congenital heart disease; heart transplant; ventricular assist device.

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References

    1. Engelings CC, Helm PC, Abdul-Khaliq H, et al. Cause of death in adults with congenital heart disease-An analysis of the German National Register for Congenital Heart Defects. Int J Cardiol. 2016;211:31-36. https://doi.org/10.1016/j.ijcard.2016.02.133.
    1. Alshawabkeh LI, Hu N, Carter KD, et al. Wait-list outcomes for adults with congenital heart disease listed for heart transplantation in the U.S. J Am Coll Cardiol. 2016;68(9):908-917. https://doi.org/10.1016/j.jacc.2016.05.082.
    1. Everitt MD, Donaldson AE, Stehlik J, et al. Would access to device therapies improve transplant outcomes for adults with congenital heart disease? Analysis of the United Network for Organ Sharing (UNOS). J Heart Lung Transplant. 2011;30(4):395-401. https://doi.org/10.1016/j.healun.2010.09.008.
    1. Cedars A, Vanderpluym C, Koehl D, Cantor R, Kutty S, Kirklin JK. An Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) analysis of hospitalization, functional status, and mortality after mechanical circulatory support in adults with congenital heart disease. J Hear Lung Transplant. 2018;37(5):619-630. https://doi.org/10.1016/j.healun.2017.11.010.
    1. Davies RR, Russo MJ, Yang J, Quaegebeur JM, Mosca RS, Chen JM. Listing and transplanting adults with congenital heart disease. Circulation. 2011;123(7):759-767. https://doi.org/10.1161/CIRCULATIONAHA.110.960260.

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