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. 2019 Nov;5(6):930-934.
doi: 10.1016/j.euf.2019.09.021. Epub 2019 Oct 15.

Examining Mannitol Use in Kidney Cancer Surgery: A Cautionary Tale of Extrapolated Surgical Data

Shiva M Nair  1 , Nicholas E Power  2 , Jonathan A Coleman  3
Affiliations

Examining Mannitol Use in Kidney Cancer Surgery: A Cautionary Tale of Extrapolated Surgical Data

Shiva M Nair et al. Eur Urol Focus. 2019 Nov.

Abstract

Mannitol for renal protection during partial nephrectomy is common but unsupported by evidence from clinical trials. The impact of mannitol on renal physiology includes both beneficial and harmful effects. Current understanding of renal ischemia reperfusion injury suggests potentially targetable processes that have a lower potential risk.

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Conflict of interest statement

Conflicts of interest: The authors have nothing to disclose.

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