Many Ways to Build a Polyp
- PMID: 31629552
- DOI: 10.1016/j.tig.2019.09.003
Many Ways to Build a Polyp
Abstract
The freshwater cnidarian Hydra has been studied for centuries for its unique regenerative capacities. Whole-body single-cell transcriptomics now reveal cellular lineages and gene regulatory networks that build the Hydra polyp. For the first time, transcription factor signatures allow direct comparison of the polyp body plan between Hydra and sea anemone.
Copyright © 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Comment on
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Stem cell differentiation trajectories in Hydra resolved at single-cell resolution.Science. 2019 Jul 26;365(6451):eaav9314. doi: 10.1126/science.aav9314. Science. 2019. PMID: 31346039 Free PMC article.
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