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Review
. 2019 Sep-Oct;33(5 Suppl. 1):45-51. Special Issue: Focus on Pediatric Nephrology.

Monosymptomatic enuresis: the therapeutic weapons

R Chimenz  1 , A Spinuzza  2 , L Cannavò  2 , V Di Benedetto  3 , M G Scuderi  3 , D Concolino  4 , G D'Angelo  5 , A Sallemi  2 , M Fusco  2 , U Cucinotta  2 , C Fede  6 , T Arrigo  2 , C Cuppari  7
Affiliations
  • PMID: 31630713
Review

Monosymptomatic enuresis: the therapeutic weapons

R Chimenz et al. J Biol Regul Homeost Agents. 2019 Sep-Oct.

Abstract

Nocturnal enuresis (NE) was defined by the World Health Organization (ICD-10) and the American Psychiatric Association (DSM-5) as bed-wetting in children aged >5 years. In cases of mental retardation, the developmental age may be equivalent to 5 years. In this review, we focus on the current knowledge about the etiology of enuresis and the most recent therapeutical options. Both non-pharmacological and pharmacological therapies are included, although the relative effectiveness of each remains uncertain. To date, motivational, alarm and drug therapies are the mainstay of treatment. Alarm therapy remains the first-line treatment modality for NE, while desmopressin is the most commonly used medical treatment.

Keywords: alarm system; desmopressin; enuresis; urinary control.

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