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Editorial
. 2019 Sep;11(Suppl 15):S1969-S1972.
doi: 10.21037/jtd.2019.07.67.

Lactate guided resuscitation-nothing is more dangerous than conscientious foolishness

Affiliations
Editorial

Lactate guided resuscitation-nothing is more dangerous than conscientious foolishness

Paul E Marik. J Thorac Dis. 2019 Sep.
No abstract available

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Conflict of interest statement

Conflicts of Interest: The author has no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Paradigm change in the management of sepsis and septic shock. Reproduced with permission from Society of Critical Care Medicine and Wolters Kluwer Health, Inc. (25).

Comment on

  • Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial.
    Hernández G, Ospina-Tascón GA, Damiani LP, Estenssoro E, Dubin A, Hurtado J, Friedman G, Castro R, Alegría L, Teboul JL, Cecconi M, Ferri G, Jibaja M, Pairumani R, Fernández P, Barahona D, Granda-Luna V, Cavalcanti AB, Bakker J; The ANDROMEDA SHOCK Investigators and the Latin America Intensive Care Network (LIVEN); Hernández G, Ospina-Tascón G, Petri Damiani L, Estenssoro E, Dubin A, Hurtado J, Friedman G, Castro R, Alegría L, Teboul JL, Cecconi M, Cecconi M, Ferri G, Jibaja M, Pairumani R, Fernández P, Barahona D, Cavalcanti AB, Bakker J, Hernández G, Alegría L, Ferri G, Rodriguez N, Holger P, Soto N, Pozo M, Bakker J, Cook D, Vincent JL, Rhodes A, Kavanagh BP, Dellinger P, Rietdijk W, Carpio D, Pavéz N, Henriquez E, Bravo S, Valenzuela ED, Vera M, Dreyse J, Oviedo V, Cid MA, Larroulet M, Petruska E, Sarabia C, Gallardo D, Sanchez JE, González H, Arancibia JM, Muñoz A, Ramirez G, Aravena F, Aquevedo A, Zambrano F, Bozinovic M, Valle F, Ramirez M, Rossel V, Muñoz P, Ceballos C, Esveile C, Carmona C, Candia E, Mendoza D, Sanchez A, Ponce D, Ponce D, Lastra J, Nahuelpán B, Fasce F, Luengo C, Medel N, Cortés C, Campassi L, Rubatto P, Horna N, Furche M, Pendino JC, Bettini L, Lovesio … See abstract for full author list ➔ Hernández G, et al. JAMA. 2019 Feb 19;321(7):654-664. doi: 10.1001/jama.2019.0071. JAMA. 2019. PMID: 30772908 Free PMC article. Clinical Trial.

References

    1. Trout HM. Proctoclysis – An experimental study. Surg Gynecol Obstet 1913;16:560-2.
    1. Hernández G, Ospina-Tascón GA, Damiani LP, et al. Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial. JAMA 2019;321:654-64. 10.1001/jama.2019.0071 - DOI - PMC - PubMed
    1. Rhodes A, Evans L, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock:2016. Crit Care Med 2017;45:486-552. 10.1097/CCM.0000000000002255 - DOI - PubMed
    1. Marik PE, Linde-Zwirble WT, Bittner EA, et al. Fluid administration in severe sepsis and septic shock, patterns and outcomes. An analysis of a large national database. Intensive Care Med 2017;43:625-32. 10.1007/s00134-016-4675-y - DOI - PubMed
    1. Marik PE. SEP-1: The Lactate Myth and Other Fairytales. Crit Care Med 2018;46:1689-90. 10.1097/CCM.0000000000003313 - DOI - PubMed