Fatty acid oxidation (FAO) metabolic switch: metastasis in lymph nodes driven by yes-associated protein (YAP) activation

Thomas Wang^{1

2}, Costa Frangou³, Jianmin Zhang¹

Affiliations

¹ Department of Cancer Genetics and Genomics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
² The University of Western Ontario, London, Ontario, Canada.
³ Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

Comment

Thomas Wang et al. Biotarget. 2019 Aug.

. 2019 Aug:3:13.

doi: 10.21037/biotarget.2019.07.03. Epub 2019 Aug 13.

Thomas Wang^{1

2}, Costa Frangou³, Jianmin Zhang¹

¹ Department of Cancer Genetics and Genomics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
² The University of Western Ontario, London, Ontario, Canada.
³ Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

No abstract available

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation.
Lee CK, Jeong SH, Jang C, Bae H, Kim YH, Park I, Kim SK, Koh GY. Lee CK, et al. Science. 2019 Feb 8;363(6427):644-649. doi: 10.1126/science.aav0173. Epub 2019 Feb 7. Science. 2019. PMID: 30733421

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