Simpson's paradox in proof-of-concept studies

Affiliations

¹ Forsyth Institute, Cambridge, MA, USA. sjanket@forsyth.org.
² Department of Public Health, University of Massachusetts, Lowell, MA, USA.
³ Department of Pathology and Laboratory Medicine, University of Toronto, Toronto, Ontario, Canada.

Comment

Sok-Ja Janket et al. Nat Med. 2019 Nov.

. 2019 Nov;25(11):1640.

doi: 10.1038/s41591-019-0624-y.

¹ Forsyth Institute, Cambridge, MA, USA. sjanket@forsyth.org.
² Department of Public Health, University of Massachusetts, Lowell, MA, USA.
³ Department of Pathology and Laboratory Medicine, University of Toronto, Toronto, Ontario, Canada.

No abstract available

Comment in

Reply to 'Simpson's paradox in proof-of-concept studies'.
Cani PD, Depommier C. Cani PD, et al. Nat Med. 2019 Nov;25(11):1640-1641. doi: 10.1038/s41591-019-0625-x. Nat Med. 2019. PMID: 31636456 No abstract available.

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study.
Depommier C, Everard A, Druart C, Plovier H, Van Hul M, Vieira-Silva S, Falony G, Raes J, Maiter D, Delzenne NM, de Barsy M, Loumaye A, Hermans MP, Thissen JP, de Vos WM, Cani PD. Depommier C, et al. Nat Med. 2019 Jul;25(7):1096-1103. doi: 10.1038/s41591-019-0495-2. Epub 2019 Jul 1. Nat Med. 2019. PMID: 31263284 Free PMC article. Clinical Trial.

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