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Review
. 2019 Nov 25;58(48):17114-17116.
doi: 10.1002/anie.201911062. Epub 2019 Oct 22.

Artificial-Intelligence-Driven Organic Synthesis-En Route towards Autonomous Synthesis?

Claire Empel  1 , Rene M Koenigs  1
Affiliations
Review

Artificial-Intelligence-Driven Organic Synthesis-En Route towards Autonomous Synthesis?

Claire Empel et al. Angew Chem Int Ed Engl. .

Abstract

AI for chemistry: Automated synthesis can now be performed using an artificial intelligence algorithm to propose the synthetic route and a robotic microfluidic platform to execute the synthesis. This Highlight describes this approach towards small-molecule synthesis and reflects on the significance of this milestone in chemistry.

Keywords: automated synthesis; flow chemistry; machine learning; total synthesis.

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