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Editorial
. 2019 Oct 21;23(1):326.
doi: 10.1186/s13054-019-2638-8.

How I optimize power to avoid VILI

John J Marini  1
Affiliations
Editorial

How I optimize power to avoid VILI

John J Marini. Crit Care. .
No abstract available

Keywords: ARDS; Energy; Mechanical ventilation; Power; VILI; Ventilator-induced lung injury.

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Conflict of interest statement

The author declares that he has no competing interests.

Figures

Fig. 1
Fig. 1
Airway pressure profile during inflation with constant flow. Under these conditions, time is an accurate surrogate for inspired volume. Ppeak and Pplat are the peak dynamic and static (“plateau”) pressures. Total PEEP is comprised of the set PEEP value and auto-PEEP. Areas A, B, and C correspond to the flow resistive, tidal elastic, and PEEP-related tidal energy components, respectively. The sum of these three areas defines the total inflation energy of the tidal cycle: FR + DP/2 + PEEPtot. Note that while PEEP-related elastic energy (area C) elevates the inflation stress and strain platform for driving pressure, its temporarily stored elastic energy dissipates completely across the exhalation valve and circuitry during deflation
See this image and copyright information in PMC

References

    1. Protti A, Maraffi T, Milesi M, Votta E, Santini A, Pugni P, Andreis DT, Nicosia F, Zannin E, Gatti S, Vaira V, Ferrero S, Gattinoni L. Role of strain rate in the pathogenesis of ventilator-induced lung edema. Crit Care Med. 2016;44(9):e838–e845. doi: 10.1097/CCM.0000000. - DOI - PubMed
    1. Garcia CS, Abreu SC, Soares RM, Prota LF, Figueira RC, Morales MM, Capelozzi VL, Zin WA, Rocco PR. Pulmonary morphofunctional effects of mechanical ventilation with high inspiratory air flow. Crit Care Med, 232. 2008;36(1):–9. - PubMed
    1. Cressoni M, Gotti M, Chiurazzi C, Massari D, Algieri I, Amini M, Cammaroto A, Brioni M, Montaruli C, Nikolla K, Guanziroli M, Dondossola D, Gatti S, Valerio V, Vergani GL, Pugni P, Cadringher P, Gagliano N, Gattinoni L. Mechanical power and development of ventilator-induced lung injury. Anesthesiology. 2016;124:1100–1108. doi: 10.1097/ALN.0000000000001056. - DOI - PubMed
    1. Marini JJ, Hotchkiss JR, Broccard AF. Bench-to-bedside review: microvascular and airspace linkage in ventilator-induced lung injury. Crit Care. 2003;7(6):435–444. doi: 10.1186/cc2392. - DOI - PMC - PubMed
    1. Marini JJ, Jaber S. Dynamic predictors of VILI risk: beyond the driving pressure. Intensive Care Med. 2016;42:1597–1600. doi: 10.1007/s00134-016-4534-x. - DOI - PubMed

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