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Comparative Study
. 1988 Apr;32(4):601-4.
doi: 10.1128/AAC.32.4.601.

In vitro activity of cefotetan compared with that of other antimicrobial agents against anaerobic bacteria

H M Wexler  1 , S M Finegold
Affiliations
Comparative Study

In vitro activity of cefotetan compared with that of other antimicrobial agents against anaerobic bacteria

H M Wexler et al. Antimicrob Agents Chemother. 1988 Apr.

Abstract

The activity of cefotetan against 430 strains of anaerobic bacteria was compared with that of cefoxitin, ceftizoxime, clindamycin, metronidazole, and chloramphenicol. Percent susceptible values for the Bacteroides fragilis group were 60, 80, 29, 86, 100, and 100%, respectively. Percent susceptible values for the B. fragilis species were 91, 92, 46, 98, 100, and 100%, respectively. Non-B. fragilis-group Bacteroides species were inhibited very well (90 to 100%) by all drugs except ceftizoxime (80%). Cefotetan and metronidazole were the most active agents against Clostridium difficile. Percent susceptible values for all strains were 72, 79, 44, 82, 93, and 98%, respectively.

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References

    1. J Antimicrob Chemother. 1982 Nov;10 Suppl C:91-7 - PubMed
    1. J Antimicrob Chemother. 1983 Jan;11 Suppl:1-9 - PubMed
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