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. 2019 Oct 21;29(20):R1091-R1093.
doi: 10.1016/j.cub.2019.08.068.

Gut Homeostasis: Active Migration of Intestinal Epithelial Cells in Tissue Renewal

Aglaja Kopf  1 , Michael Sixt  2
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Gut Homeostasis: Active Migration of Intestinal Epithelial Cells in Tissue Renewal

Aglaja Kopf et al. Curr Biol. .
Free article

Abstract

A new study has uncovered a previously unknown feature of intestinal epithelial cells during gut homeostasis. Biophysical modeling combined with quantitative tissue imaging indicates that epithelial cells actively migrate up the gut villus, challenging the current concept of passive tissue renewal.

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