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Comment
. 2020 Jan 15;26(2):325-327.
doi: 10.1158/1078-0432.CCR-19-2975. Epub 2019 Oct 22.

Space for Calaspargase? A New Asparaginase for Acute Lymphoblastic Leukemia

Glen Lew  1
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Space for Calaspargase? A New Asparaginase for Acute Lymphoblastic Leukemia

Glen Lew. Clin Cancer Res. .

Abstract

In December 2018, the FDA approved calaspargase pegol-mknl (Asperlas, Servier Pharmaceuticals) for acute lymphoblastic leukemia (ALL) in children and young adults up to age 21. Asparaginase is a critical component in the treatment of ALL, but the niche for calaspargase within current treatment protocols is unclear.See related article by Li et al., p. 328.

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