Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Oct 17;94(4):497-498.
doi: 10.1590/abd1806-4841.20198453. eCollection 2019.

Nodular amelanotic melanoma

Thadeu Santos Silva  1 , Luciana Rebouças de Araujo  2 , Gustavo Baptista de Almeida Faro  1 , Geise Rezende Paiva  3
Affiliations
Case Reports

Nodular amelanotic melanoma

Thadeu Santos Silva et al. An Bras Dermatol. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None.

Figures

Figure 1
Figure 1
Tumoral lesion approximately 4cm in diameter, located on the lower back, with surrounding erythema
Figure 2
Figure 2
Histopathology: Confluence of nests of large, atypical mela nocytes. The cells are irregular in size, shape, and spacing. Many have hyperchromatic and pleomorphic nuclei and pigmented cytoplasm (Hematoxylin & eosin, x100)
Figure 3
Figure 3
Immunohistochemistry: expression of HMB45 (HMB45, x100)
See this image and copyright information in PMC

References

    1. Thomas NE, Kricker A, Waxweiler WT, Dillon PM, Busman KJ, From L, et al. Genes, Environment, and Melanoma (GEM) Study Group Comparison of clinicopathologic features and survival of histopathologically amelanotic and pigmented melanomas: a population-based study. JAMA Dermatol. 2014;150:1306–1314. - PMC - PubMed
    1. Cheung WL, Patel RR, Leonard A, Firoz B, Meehan SA. Amelanotic melanoma: a detailed morphologic analysis with clinicopathologic correlation of 75 cases. J Cutan Pathol. 2012;39:33–39. - PubMed
    1. Jaimes N, Braun RP, Thomas L, Marghoob AA. Clinical and dermoscopic characteristics of amelanotic melanomas that are not of the nodular subtype. J Eur Acad Dermatol Venereol. 2012;26:591–596. - PubMed
    1. Mendes MS, Costa MC, Gomes CM, de Araújo LC, Takano GH. Amelanotic metastatic cutaneous melanoma. An Bras Dermatol. 2013;88:989–991. - PMC - PubMed

LinkOut - more resources