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. 2019 Oct 24;14(10):e0221775.
doi: 10.1371/journal.pone.0221775. eCollection 2019.

Global incidence of prostate cancer in developing and developed countries with changing age structures

Jeremy Y C Teoh  1 , Hoyee W Hirai  2 , Jason M W Ho  2   3 , Felix C H Chan  2 , Kelvin K F Tsoi  2   3 , Chi Fai Ng  1
Affiliations

Global incidence of prostate cancer in developing and developed countries with changing age structures

Jeremy Y C Teoh et al. PLoS One. .

Abstract

To investigate the global incidence of prostate cancer with special attention to the changing age structures. Data regarding the cancer incidence and population statistics were retrieved from the International Agency for Research on Cancer in World Health Organization. Eight developing and developed jurisdictions in Asia and the Western countries were selected for global comparison. Time series were constructed based on the cancer incidence rates from 1988 to 2007. The incidence rate of the population aged ≥ 65 was adjusted by the increasing proportion of elderly population, and was defined as the "aging-adjusted incidence rate". Cancer incidence and population were then projected to 2030. The aging-adjusted incidence rates of prostate cancer in Asia (Hong Kong, Japan and China) and the developing Western countries (Costa Rica and Croatia) had increased progressively with time. In the developed Western countries (the United States, the United Kingdom and Sweden), we observed initial increases in the aging-adjusted incidence rates of prostate cancer, which then gradually plateaued and even decreased with time. Projections showed that the aging-adjusted incidence rates of prostate cancer in Asia and the developing Western countries were expected to increase in much larger extents than the developed Western countries.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1
(A) Incidence rates of age ≥65. (B) Aging-adjusted incidence rates of age ≥65.
Fig 2
Fig 2
(A) Projections of incidence rates of age ≥65. (B) Projections of aging-adjusted incidence rates of age ≥65.
See this image and copyright information in PMC

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