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Comment
. 2019 Oct 23;104(2):186-188.
doi: 10.1016/j.neuron.2019.10.005.

Dynamics of Neuronal Activity in the Cortical Column during Behavior: Both Neuron Type and Layers Matter

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Comment

Dynamics of Neuronal Activity in the Cortical Column during Behavior: Both Neuron Type and Layers Matter

Benjamin Schuman et al. Neuron. .

Abstract

In this issue of Neuron, Yu et al. (2019) reveal the activity of excitatory cells and GABAergic inhibitory interneurons throughout the neocortical column during active sensation. The authors utilized a combination of spike waveform analysis and genetic tools to identify cell types, demonstrating their distinct patterns of recruitment during behavior.

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Figures

Figure 1.
Figure 1.. The Flow of Thalamocortical Information in the Mouse Barrel Cortex during Active Sensation
Schematic of the functional connectivity between cortical excitatory cells (E), GABAergic interneurons, and VPM thalamocortical neurons (A) and the median touch-evoked response times (ms) for cells across the cortical column arranged horizontally in order of activation time (B). FS neurons track thalamic input and mediate feedforward inhibition; SST neurons monitor the activity of local excitatory neurons and provide feedback inhibition.

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