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. 2020 Mar;182(3):788-789.
doi: 10.1111/bjd.18630. Epub 2019 Dec 13.

Update on pachyonychia congenita research

Affiliations

Update on pachyonychia congenita research

T Funk et al. Br J Dermatol. 2020 Mar.
No abstract available

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References

    1. Zieman AG, Coulombe PA. Pathophysiology of pachyonychia congenita-associated palmoplantar keratoderma: new insights into skin epithelial homeostasis and avenues for treatment. Br J Dermatol 2020; 182:564-73.
    1. Maruthappu T, Chikh A, Fell B et al. Rhomboid family member 2 regulates cytoskeletal stress-associated keratin 16. Nat Commun 2017; 8:14174.
    1. Eldirany SA, Ho M, Hinbest AJ et al. Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly. EMBO J 2019; 38:e100741.
    1. Spörrer M, Prochnicki A, Tölle RC et al. Treatment of keratinocytes with 4-phenylbutyrate in epidermolysis bullosa: lessons for therapies in keratin disorders. EBioMedicine 2019; 44:502-15.
    1. Hickerson RP, Flores MA, Leake D et al. Use of self-delivery siRNAs to inhibit gene expression in an organotypic pachyonychia congenita model. J Invest Dermatol 2011; 131:1037-44.

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