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Comment
. 2019 Nov 15;86(10):e33-e35.
doi: 10.1016/j.biopsych.2019.09.012.

Stress and Neurodevelopment in Adolescent Depression

Tiffany C Ho  1
Affiliations
Comment

Stress and Neurodevelopment in Adolescent Depression

Tiffany C Ho. Biol Psychiatry. .
No abstract available

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Conflict of interest statement

The author reports no biomedical financial interests or potential conflicts of interest.

Figures

Figure 1.
Figure 1.
Conceptual model of how stress acceleration may lead to depressive disorders by shortening sensitive periods for developing systems. While prematurely ending a sensitive period may be protective against the influence of negative experiences on brain development, a potential cost is the absence of positive experiences that scaffold optimal development.
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References

    1. Breslau J, Gilman SE, Stein BD, Ruder T, Gmelin T, Miller E (2017): Sex differences in recent first-onset depression in an epidemiological sample of adolescents. Transl Psychiatry 7:e1139. - PMC - PubMed
    1. Gee DG, Casey BJ (2015): The impact of developmental timing for stress and recovery. Neurobiol Stress 1:184–194. - PMC - PubMed
    1. McLaughlin KA, Sheridan MA, Nelson CA (2017): Neglect as a violation of species-expectant experience: Neurodevelopmental consequences. Biol Psychiatry 82:462–471. - PMC - PubMed
    1. Bartlett EA, Klein DN, Li K, DeLorenzo C, Kotov R, Perlman G (2019): Depression severity over 27 months in adolescent girls is predicted by stress-linked cortical morphology. Biol Psychiatry 86:769–778. - PMC - PubMed
    1. Teicher MH, Samson JA, Anderson CM, Ohashi K (2016): The effects of childhood maltreatment on brain structure, function and connectivity. Nat Rev Neurosci 17:652–666. - PubMed

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