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Comment
. 2019 Nov;96(5):1066-1068.
doi: 10.1016/j.kint.2019.07.003.

"Permissive AKI" with treatment of heart failure

Chirag R Parikh  1 , Steven G Coca  2
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"Permissive AKI" with treatment of heart failure

Chirag R Parikh et al. Kidney Int. 2019 Nov.
Free article

Abstract

Renin-angiotensin-aldosterone system inhibitors have proven clinical benefit in management of patients with heart failure with reduced ejection fraction. However, there are no guidelines to manage decline in kidney function that occurs with initiation and titration of renin-angiotensin-aldosterone system agents during management of heart failure. We discuss the complex interplay of kidney function and heart failure in the presence of renin-angiotensin-aldosterone system agents and suggest a clinical algorithm for management of acute decline in kidney function.

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