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Review
. 2019 Dec;105(23):1832-1840.
doi: 10.1136/heartjnl-2019-315560. Epub 2019 Oct 24.

Myocardial fibrosis: why image, how to image and clinical implications

Rong Bing  1 , Marc Richard Dweck  2
Affiliations
Review

Myocardial fibrosis: why image, how to image and clinical implications

Rong Bing et al. Heart. 2019 Dec.
No abstract available

Keywords: cardiac magnetic resonance (CMR) imaging; myocardial disease.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
T1 mapping in cardiovascular magnetic resonance modified Look-Locker inversion recovery sequence. A sequence of three inversion recovery experiments are performed with images acquired and ordered according to inversion times. Signals are then used to plot a T1 recovery curve. The T1 value is the time when T1 recovery is 63% complete. T1 values are then used to create a voxel map. Adapted from Everett et al.
Figure 2
Figure 2
Ischaemic cardiomyopathy extensive anteroseptal myocardial infarction. Two-chamber (left) and short-axis (right) views demonstrate transmural late gadolinium enhancement in the left anterior descending artery territory with associated wall thinning, suggesting no viability.
Figure 3
Figure 3
Non-ischaemic dilated cardiomyopathy. Four-chamber (left) and short-axis (right) views demonstrate anteroseptal and inferoseptal late gadolinium enhancement in a typical non-ischaemic (mid-wall) distribution. Note sparing of the subendocardium.
Figure 4
Figure 4
Aortic stenosis myocardial fibrosis in aortic stenosis. There is non-ischaemic late gadolinium enhancement in the basal inferolateral and inferior wall, where the subendocardium is spared (red arrow).
Figure 5
Figure 5
Hypertrophic cardiomyopathy examples of hypertrophic cardiomyopathy with typical septal hypertrophy (right) and an apical variant (left). Patchy non-infarct late gadolinium enhancement is seen within the regions of wall thickening.
Figure 6
Figure 6
Myocarditis. Three-chamber (left) and short-axis (right) examples of patchy, non-infarct, mid-wall late gadolinium enhancement in the anterolateral and inferolateral walls of a patient with chronic myocarditis (3 months after the onset of symptoms). Note that these findings are non-specific.
Figure 7
Figure 7
Cardiac amyloidosis and sarcoidosis. Left: cardiac amyloidosis. Note the black blood pool and diffuse late gadolinium enhancement within the abnormal myocardium. Right: cardiac sarcoidosis. The distribution of late gadolinium enhancement in cardiac sarcoidosis is variable. Here, there is a large burden of confluent enhancement in the inferior and inferolateral wall.
See this image and copyright information in PMC

References

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