Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Sep;34(5):565-571.
doi: 10.1111/ppe.12598. Epub 2019 Oct 24.

Survival and early complications of preterm infants with birthweight less than 500 grams during a 10-year period in Hungary

Péter Varga  1 , Botond Berecz  1 , Zsófia Magyar  1 , Barbara Pete  1 , Éva Romicsné Görbe  1 , Zsófia Anna Dombi  1 , Lilla Sassi  1 , Eszter Fanczal  1 , Nándor Ács  1 , László Kornya  2 , József Gábor Joó  1 , Andrea Valek  3 , Ágnes Harmath  1 , Ákos Gasparics  1
Affiliations

Survival and early complications of preterm infants with birthweight less than 500 grams during a 10-year period in Hungary

Péter Varga et al. Paediatr Perinat Epidemiol. 2020 Sep.

Abstract

Background: There are limited data available on the survival and early complications of preterm infants with less than 500 g birthweight. To estimate the outcomes for these infants, it is important for caregivers to be aware of perinatal factors that may affect survival.

Objectives: We assessed the mortality and certain early complications of preterm infants born with less than 500 g in Hungary between 2006 and 2015.

Methods: We reviewed data of 486 infants from the database of the Hungarian Central Statistical Office and in parallel of 407 infants from the "NICU database." The study period was divided into two epochs: 2006-2010 and 2011-2015.

Results: The survival was 27.1% in the first epoch and 39.1% in the second epoch, and the incidence of early complications was slightly higher in the second epoch. In the surviving group (first and second epoch combined), gestational age (25.1 vs 23.7 weeks), birthweight (458 vs 447 g) antenatal steroid treatment (66.3% vs 52.3%), surfactant therapy (95.1% vs 84.3%), median Apgar scores (6 vs 3 and 8 vs 5 at 1 and 5 minutes, respectively) and proportion of caesarean delivery (89.3% versus 68.5%) were higher than in the non-surviving group (first and second epoch combined). The proportion of multiple births was lower in the surviving group (15.7% vs 33.4%).

Conclusions: Survival of infants with less than 500 g improved between 2006-2010 and 2011-2015 in Hungary. The slightly higher occurrence of early complications might be associated with improving survival.

Keywords: early complications; extremely low birthweight; outcome; preterm infants; survival.

PubMed Disclaimer

References

REFERENCES

    1. Fanaroff JM, Hascoet JM, Hansen TW, et al. The ethics and practice of neonatal resuscitation at the limits of viability: an international perspective. Acta Paediatr. 2014;103:701-708.
    1. World Health Organization; March of Dimes; The Partnership for Maternal NCHStC. Born too soon: the global action report on preterm birth. 2012; Available from: http://www.who.int/pmnch/media/news/2012/preterm_birth_report/en/index.html.
    1. Gillone J, Banait N, Miller N, Ward Platt M, Harigopal S. Outcomes of infants with a birthweight less than or equal to 500 g in Northern England: 15 years experience. Acta Paediatr. 2018;107:223-226.
    1. Upadhyay K, Pourcyrous M, Dhanireddy R, Talati AJ. Outcomes of neonates with birth weight500 g: a 20-year experience. J Perinatol. 2015;35:768-772.
    1. Hsieh WS, Jeng SF, Hung YL, Chen PC, Chou HC, Tsao PN. Outcome and hospital cost for infants weighing less than 500 grams: a tertiary centre experience in Taiwan. J Paediatr Child Health. 2007;43:627-631.

MeSH terms

LinkOut - more resources