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Review
. 2019 Dec;48(4):751-764.
doi: 10.1016/j.ecl.2019.08.004. Epub 2019 Sep 18.

Pseudopheochromocytoma

Divya Mamilla  1 , Melissa K Gonzales  1 , Murray D Esler  2 , Karel Pacak  3
Affiliations
Review

Pseudopheochromocytoma

Divya Mamilla et al. Endocrinol Metab Clin North Am. 2019 Dec.

Abstract

Pseudopheochromocytoma manifests as severe, symptomatic paroxysmal hypertension without significant elevation in catecholamine and metanephrine levels and lack of evidence of tumor in the adrenal gland. The clinical manifestations are similar but not identical to those in excess circulating catecholamines. The underlying symptomatic mechanism includes augmented cardiovascular responsiveness to catecholamines alongside heightened sympathetic nervous stimulation. The psychological characteristics are probably attributed to the component of repressed emotions related to a past traumatic episode or repressive coping style. Successful management can be achieved by strong collaboration between a hypertension specialist and a psychiatrist or psychologist with expertise in cognitive-behavioral panic management.

Keywords: Hypertension; Paroxysm; Pheochromocytoma; Pseudopheochromocytoma; Spell.

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Figures

Figure 1.
Figure 1.
Pathogenesis of Pseudopheochromocytoma *Probably sudden and brisk increase in there activity #Extra-adrenal pheochromocytoma are called as paraganglioma BP blood pressure; CNS central nervous system; HR heart rate; PHEO pheochromocytoma; PTSD post-traumatic stress disorder
See this image and copyright information in PMC

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