Treatment of sepsis-induced acute kidney injury in the ICU: the therapeutic targets do not seem to be established yet

Jean-Pierre Quenot^{1

2

3

4

5

6}, Auguste Dargent^{1

2}, Audrey Large¹, Jean-Baptiste Roudaut¹, Pascal Andreu¹, Saber Barbar^{7

8}

Affiliations

¹ Service de Médecine Intensive-Réanimation, CHU Dijon Bourgogne, France.
² INSERM, U1231, Equipe Lipness, Dijon, France.
³ Université Bourgogne-Franche-Comté, UMR1231 Lipides, Nutrition, Cancer, équipe Lipness, Dijon, France.
⁴ LipSTIC LabEx, Fondation de coopération scientifique Bourgogne-Franche-Comté, Dijon, France.
⁵ INSERM, CIC 1432, Module Epidémiologie Clinique, Dijon, France.
⁶ CHU Dijon-Bourgogne, Centre d'Investigation Clinique, Module Epidémiologie Clinique/Essais Cliniques, Dijon, France.
⁷ Service de Réanimation, CHU de Nîmes, France.
⁸ Université de Montpellier, Faculté de Médecine de Montpellier-Nîmes, EA 2992, Nîmes, France.

Editorial

Jean-Pierre Quenot et al. Ann Transl Med. 2019 Sep.

. 2019 Sep;7(Suppl 6):S181.

doi: 10.21037/atm.2019.07.66.

Jean-Pierre Quenot^{1

2

3

4

5

6}, Auguste Dargent^{1

2}, Audrey Large¹, Jean-Baptiste Roudaut¹, Pascal Andreu¹, Saber Barbar^{7

8}

¹ Service de Médecine Intensive-Réanimation, CHU Dijon Bourgogne, France.
² INSERM, U1231, Equipe Lipness, Dijon, France.
³ Université Bourgogne-Franche-Comté, UMR1231 Lipides, Nutrition, Cancer, équipe Lipness, Dijon, France.
⁴ LipSTIC LabEx, Fondation de coopération scientifique Bourgogne-Franche-Comté, Dijon, France.
⁵ INSERM, CIC 1432, Module Epidémiologie Clinique, Dijon, France.
⁶ CHU Dijon-Bourgogne, Centre d'Investigation Clinique, Module Epidémiologie Clinique/Essais Cliniques, Dijon, France.
⁷ Service de Réanimation, CHU de Nîmes, France.
⁸ Université de Montpellier, Faculté de Médecine de Montpellier-Nîmes, EA 2992, Nîmes, France.

No abstract available

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated Acute Kidney Injury: A Randomized Clinical Trial.
Pickkers P, Mehta RL, Murray PT, Joannidis M, Molitoris BA, Kellum JA, Bachler M, Hoste EAJ, Hoiting O, Krell K, Ostermann M, Rozendaal W, Valkonen M, Brealey D, Beishuizen A, Meziani F, Murugan R, de Geus H, Payen D, van den Berg E, Arend J; STOP-AKI Investigators. Pickkers P, et al. JAMA. 2018 Nov 20;320(19):1998-2009. doi: 10.1001/jama.2018.14283. JAMA. 2018. PMID: 30357272 Free PMC article. Clinical Trial.

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