Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Sep;5(Suppl 2):S160-S165.
doi: 10.21037/jss.2019.09.33.

Anesthesia and postoperative pain control-multimodal anesthesia protocol

Affiliations
Review

Anesthesia and postoperative pain control-multimodal anesthesia protocol

Alisha Bhatia et al. J Spine Surg. 2019 Sep.

Abstract

Multimodal analgesia (MMA) involves the use of additive or synergistic combinations of analgesics to achieve clinically required analgesia while minimizing significant side effects associated with higher dose of a single equianalgesic medication such as an opioid analgesic. MMA generally involves optimizing non-opioid pharmacologic and non-pharmacologic interventions and reserving opioid use to treat breakthrough pain. Patients receiving medications via MMA protocols are likely to have lower opioid consumption compared to those managed using primarily IV opioid patient-controlled analgesia. MMA pain management strategies have become important components of enhanced recovery after surgery (ERAS) protocols in an effort to optimize care by standardizing analgesic medications in the perioperative setting while minimizing adverse effects and improving quality and patient outcomes. Successful implementation of a MMA requires the input and cooperation of all of the stakeholders including the caregivers as well as the patients. Health system benefits can also be realized from the implementation of an effective MMA, as fewer opioid related side effects can improve patient recovery and lead to faster discharge and improved utilization of resources.

Keywords: Multimodal analgesia; anesthesia; enhanced recovery after surgery (ERAS); minimally invasive spine surgery; narcotics consumption; pain control.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

References

    1. Sharma S, Balireddy RK, Vorenkamp KE, et al. Beyond opioid patient-controlled analgesia: a systematic review of analgesia after major spine surgery. Reg Anesth Pain Med 2012;37:79-98. 10.1097/AAP.0b013e3182340869 - DOI - PubMed
    1. Rajpal S, Gordon DB, Pellino TA, et al. Comparison of perioperative oral multimodal analgesia versus IV PCA for spine surgery. J Spinal Disord Tech 2010;23:139-45. 10.1097/BSD.0b013e3181cf07ee - DOI - PubMed
    1. Bohl DD, Louie PK, Shah N, et al. Multimodal versus patient-controlled analgesia after an anterior cervical decompression and fusion. Spine (Phila Pa 1976) 2016;41:994-8. 10.1097/BRS.0000000000001380 - DOI - PubMed
    1. van Tulder M, Becker A, Bekkering T, et al. Chapter 3. European guidelines for the management of acute nonspecific low back pain in primary care. Eur Spine J 2006;15 Suppl 2:S169-91. 10.1007/s00586-006-1071-2 - DOI - PMC - PubMed
    1. Friedman B, Dym AA, Davitt M, et al. Naproxen with cyclobenzaprine, oxycodone/acetaminophen, or placebo for treating acute low back pain. JAMA 2015;314:1572-80. 10.1001/jama.2015.13043 - DOI - PubMed