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. 2019 Dec 15;200(12):1466-1471.
doi: 10.1164/rccm.201910-1999PP.

A Perspective: Division of Lung Diseases at Fifty

Collaborators, Affiliations

A Perspective: Division of Lung Diseases at Fifty

Gail G Weinmann et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
Graphical history of NHLBI’s Division of Lung Diseases (DLD). (A) Time trend of DLD funding of extramural research for the period 1969–2018. (B) Selected representative initiatives developed and funded by DLD that reflect the evolving nature of pulmonary research over the past five decades. Initially, DLD focused on establishing a robust research community at the cutting edge of science by steering investigators from physiology to more basic and cellular work and encouraging research training (not shown). Early initiatives focused on identifying lung cells and basic mechanisms, gradually over time focusing on particular diseases and conditions. In the second era, starting in the early 1990s, DLD addressed the paucity of investigator-initiated clinical trials in lung disease by releasing initiatives for clinical research networks. These clinical trial results revealed the heterogeneity of responses to treatment and led to the third and current era with the development of programs defining phenotype–genotype relationships as a first step toward identifying targets for novel and personalized treatments. Full names of the programs identified by acronyms in the figure are given in the appendix in the online supplement.

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